FRMD4A and TRAF3IP1

Data Source:
BioGRID (two hybrid)

		FRMD4A	TRAF3IP1
Description		FERM domain containing 4A	TRAF3 interacting protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Adherens Junction Bicellular Tight Junction	Centrosome Cilium Axoneme Intraciliary Transport Particle B Ciliary Transition Zone Ciliary Basal Body Ciliary Tip Ciliary Base
	Molecular Function	Protein-macromolecule Adaptor Activity	Protein Binding Microtubule Binding
	Biological Process	Negative Regulation Of Protein Secretion Positive Regulation Of Protein Secretion Establishment Of Epithelial Cell Polarity	Morphogenesis Of A Polarized Epithelium Kidney Development Negative Regulation Of Protein Phosphorylation Negative Regulation Of Protein-containing Complex Assembly Negative Regulation Of Type I Interferon Production Intraciliary Transport Involved In Cilium Assembly Intraciliary Transport Negative Regulation Of Defense Response To Virus Cilium Assembly Regulation Of Microtubule Cytoskeleton Organization
Pathways			Intraflagellar transport Intraflagellar transport
Drugs
Diseases
GWAS		Adiponectin levels ( 26299439) Alcohol consumption (max-drinks) ( 29460428) Alzheimer's disease ( 22430674) Chronic obstructive pulmonary disease ( 32222710) Craniofacial microsomia ( 26853712) Depressive symptoms x dependent stressful life events interaction (2df test) ( 30718454) Gut microbiota alpha diversity (PD_whole_tree index) ( 33208821) Hematocrit ( 32888494) Hemoglobin ( 32888494) Knee osteoarthritis ( 27696742) Non-lobar intracerebral hemorrhage (MTAG) ( 31430377) Obstetric antiphospholipid syndrome ( 28424481) Rapid automised naming of digits ( 30741946) Red blood cell count ( 32888494) Red cell distribution width ( 32888494 27863252 28957414) RR interval (heart rate) ( 20031603) Takayasu arteritis ( 25604533)	Chronotype ( 30696823) FEV1 ( 30804560) Intraocular pressure ( 29617998 29785010 30054594) Iris characteristics ( 21835309) Lung function (FEV1/FVC) ( 28166213 30804560) Metabolite levels ( 23823483) Morning person ( 30696823) Refractive astigmatism ( 30306274) Refractive error ( 32231278) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		2 interacting genes: TRAF3IP1 YEATS4	29 interacting genes: ABI2 APP CCDC93 CCNA2 CDC5L DISC1 DMD DST DTNBP1 EXOC1 FRMD4A GOLGA4 IL13RA1 IMMT MACF1 OLFM1 SFR1 SGF29 SMC2 SMC3 SMC4 SNAP91 SPTBN1 TAB2 TRAF3 TRAF6 TRAK1 UBXN10 WAC
Entrez ID		55691	26146
HPRD ID		13553	09571
Ensembl ID		ENSG00000151474	ENSG00000204104
Uniprot IDs		Q9NW91 Q9P2Q2	Q8TDR0
PDB IDs			2EQO
Enriched GO Terms of Interacting Partners?
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