TSEN2 and RANBP10

Data Source:
HPRD (two hybrid)

		TSEN2	RANBP10
Description		tRNA splicing endonuclease subunit 2	RAN binding protein 10
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	TRNA-intron Endonuclease Complex Nucleoplasm Nucleolus Centrosome Cytosol	Ubiquitin Ligase Complex Nucleus Cytoplasm Cytosol
	Molecular Function	TRNA-intron Endonuclease Activity Nucleic Acid Binding Protein Binding Lyase Activity	Protein Binding
	Biological Process	TRNA-type Intron Splice Site Recognition And Cleavage TRNA Splicing, Via Endonucleolytic Cleavage And Ligation MRNA Processing RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	Cytoskeleton Organization Cell Surface Receptor Signaling Pathway
Pathways		tRNA processing in the nucleus	MET activates RAS signaling
Drugs
Diseases		Pontocerebellar hypoplasia
GWAS		Systemic lupus erythematosus ( 28714469) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Empathy quotient ( 29527006) HDL cholesterol ( 25961943) Hematocrit ( 32888494 27863252) Hemoglobin concentration ( 27863252) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		7 interacting genes: CADPS CTAG2 GABPB2 RANBP10 TAX1BP1 TEPSIN TSEN54	16 interacting genes: CACHD1 CNTNAP4 CTAG1A CTAG1B IGFBP6 IGSF1 MAEA MAGEA11 MEGF10 MET NEDD4 NEDD4L PRKCG RAN THSD7B TSEN2
Entrez ID		80746	57610
HPRD ID		10576	15207
Ensembl ID		ENSG00000154743	ENSG00000141084
Uniprot IDs		A0A024R2G3 Q8NCE0	B3KP49 Q6VN20 R4GMX8
PDB IDs
Enriched GO Terms of Interacting Partners?
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