RANBP10 and TSEN2

Data Source:
HPRD (two hybrid)

		RANBP10	TSEN2
Description		RAN binding protein 10	tRNA splicing endonuclease subunit 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Cytoplasm Cytosol	TRNA-intron Endonuclease Complex Nucleoplasm Nucleolus Centrosome Cytosol
	Molecular Function	Protein Binding	TRNA-intron Endonuclease Activity Nucleic Acid Binding Protein Binding Lyase Activity
	Biological Process	Cytoskeleton Organization Cell Surface Receptor Signaling Pathway	TRNA-type Intron Splice Site Recognition And Cleavage TRNA Splicing, Via Endonucleolytic Cleavage And Ligation MRNA Processing RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways		MET activates RAS signaling	tRNA processing in the nucleus
Drugs
Diseases			Pontocerebellar hypoplasia
GWAS		Empathy quotient ( 29527006) HDL cholesterol ( 25961943) Hematocrit ( 32888494 27863252) Hemoglobin concentration ( 27863252) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)	Systemic lupus erythematosus ( 28714469) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		16 interacting genes: CACHD1 CNTNAP4 CTAG1A CTAG1B IGFBP6 IGSF1 MAEA MAGEA11 MEGF10 MET NEDD4 NEDD4L PRKCG RAN THSD7B TSEN2	7 interacting genes: CADPS CTAG2 GABPB2 RANBP10 TAX1BP1 TEPSIN TSEN54
Entrez ID		57610	80746
HPRD ID		15207	10576
Ensembl ID		ENSG00000141084	ENSG00000154743
Uniprot IDs		B3KP49 Q6VN20 R4GMX8	A0A024R2G3 Q8NCE0
PDB IDs
Enriched GO Terms of Interacting Partners?
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