SLC19A3 and TMEM14A

Data Source:
BioGRID (two hybrid)

		SLC19A3	TMEM14A
Description		solute carrier family 19 member 3	transmembrane protein 14A
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Endoplasmic Reticulum Membrane Integral Component Of Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding Thiamine Transmembrane Transporter Activity	Protein Binding
	Biological Process	Thiamine-containing Compound Metabolic Process Transmembrane Transport Thiamine Transmembrane Transport	Mitochondrial Transport Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Pathways		Vitamin B1 (thiamin) metabolism
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Asthma ( 31959851 30929738) Asthma (childhood onset) ( 30929738) Asthma onset (childhood vs adult) ( 30929738) Obesity-related traits ( 23251661)	Metabolite levels ( 23823483) Perceived intensity of neohesperidin dihydrochalcone ( 31005972) Response to hepatitis B vaccine ( 29534301)
Interacting Genes		15 interacting genes: C3orf38 C4orf3 CREB3 CREB3L4 CYB561 CYP4F2 FXYD6-FXYD2 LAT PLPPR2 TAB2 THBD TMEM14A TMEM14B TMEM242 ZFPL1	35 interacting genes: AQP6 CLN8 CPLX4 CREB3 CREB3L1 CXCR3 ERBB3 ERBB4 ERGIC3 ERMAP IER3IP1 KCNK5 LMNA LRCH1 LXN MMGT1 MTNR1A MTNR1B MUC1 NEMP1 PDZK1IP1 SCN3B SERINC2 SLC10A6 SLC18A1 SLC19A3 SLC7A1 SSMEM1 TMEM14B TMEM179B TMEM31 TMEM51 TMEM80 TMEM86B USP18
Entrez ID		80704	28978
HPRD ID		07311	15522
Ensembl ID		ENSG00000135917	ENSG00000096092
Uniprot IDs		Q9BZV2	Q9Y6G1
PDB IDs			2LOO 2LOP
Enriched GO Terms of Interacting Partners?
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