TMEM14A and LRCH1

Data Source:
BioGRID (two hybrid)

		TMEM14A	LRCH1
Description		transmembrane protein 14A	leucine rich repeats and calponin homology domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane Mitochondrial Membrane	Cytoplasm
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Mitochondrial Transport Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway	Negative Regulation Of GTPase Activity Cellular Response To Chemokine Negative Regulation Of T Cell Migration
Pathways
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Perceived intensity of neohesperidin dihydrochalcone ( 31005972) Response to hepatitis B vaccine ( 29534301)	Brain morphology (MOSTest) ( 32665545) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Immature fraction of reticulocytes ( 32888494) Ischemic stroke ( 29531354) Mean platelet volume ( 32888494 27863252) Mosquito bite size ( 28199695) Optic disc size ( 31809533) Platelet count ( 32888494) Platelet distribution width ( 32888494 27863252) PR interval ( 30679814 30046033 32439900) PR segment ( 24850809) Pulse pressure ( 30578418) QRS complex (12-leadsum) ( 27659466) Stroke ( 29531354) Systolic blood pressure ( 30224653)
Interacting Genes		35 interacting genes: AQP6 CLN8 CPLX4 CREB3 CREB3L1 CXCR3 ERBB3 ERBB4 ERGIC3 ERMAP IER3IP1 KCNK5 LMNA LRCH1 LXN MMGT1 MTNR1A MTNR1B MUC1 NEMP1 PDZK1IP1 SCN3B SERINC2 SLC10A6 SLC18A1 SLC19A3 SLC7A1 SSMEM1 TMEM14B TMEM179B TMEM31 TMEM51 TMEM80 TMEM86B USP18	2 interacting genes: TMEM14A TMEM14B
Entrez ID		28978	23143
HPRD ID		15522	14307
Ensembl ID		ENSG00000096092	ENSG00000136141
Uniprot IDs		Q9Y6G1	Q9Y2L9
PDB IDs		2LOO 2LOP
Enriched GO Terms of Interacting Partners?
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