TMEM14A and LXN

Data Source:
BioGRID (two hybrid)

		TMEM14A	LXN
Description		transmembrane protein 14A	latexin
Image
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane Mitochondrial Membrane	Extracellular Space Cytoplasm
	Molecular Function	Protein Binding	Protein Binding Metalloendopeptidase Inhibitor Activity Heparin Binding
	Biological Process	Mitochondrial Transport Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway	Inflammatory Response Negative Regulation Of Endopeptidase Activity Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain
Pathways
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Perceived intensity of neohesperidin dihydrochalcone ( 31005972) Response to hepatitis B vaccine ( 29534301)	Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143)
Interacting Genes		35 interacting genes: AQP6 CLN8 CPLX4 CREB3 CREB3L1 CXCR3 ERBB3 ERBB4 ERGIC3 ERMAP IER3IP1 KCNK5 LMNA LRCH1 LXN MMGT1 MTNR1A MTNR1B MUC1 NEMP1 PDZK1IP1 SCN3B SERINC2 SLC10A6 SLC18A1 SLC19A3 SLC7A1 SSMEM1 TMEM14B TMEM179B TMEM31 TMEM51 TMEM80 TMEM86B USP18	25 interacting genes: BOC CA3 COX6A1 CYBC1 DNAJC11 DPYD FCGR3A GSG1L IGSF11 MAGEA8 MCMDC2 NSMF PAX6 PPP1R3C RNF4 SHKBP1 SPAG7 TMEM14A TRAIP TRIM39 YIF1B ZCCHC17 ZKSCAN4 ZNF430 ZNF679
Entrez ID		28978	56925
HPRD ID		15522	14327
Ensembl ID		ENSG00000096092	ENSG00000079257
Uniprot IDs		Q9Y6G1	Q9BS40
PDB IDs		2LOO 2LOP	2BO9
Enriched GO Terms of Interacting Partners?
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