AP3S1 and SLC30A3

Data Source:
HPRD (in vitro, in vivo)

		AP3S1	SLC30A3
Description		adaptor related protein complex 3 subunit sigma 1	solute carrier family 30 member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus AP-type Membrane Coat Adaptor Complex AP-3 Adaptor Complex Transport Vesicle Cytoplasmic Vesicle Membrane Intracellular Membrane-bounded Organelle Axon Cytoplasm	Cytoplasm Lysosomal Membrane Endosome Late Endosome Plasma Membrane Integral Component Of Plasma Membrane Synaptic Vesicle Membrane Integral Component Of Synaptic Vesicle Membrane Late Endosome Membrane Neuron Projection Hippocampal Mossy Fiber Hippocampal Mossy Fiber To CA3 Synapse Glutamatergic Synapse
	Molecular Function	Protein Binding	Zinc Ion Transmembrane Transporter Activity Protein Binding ABC-type Zinc Transporter Activity
	Biological Process	Intracellular Protein Transport Anterograde Axonal Transport Insulin Receptor Signaling Pathway Vesicle-mediated Transport Anterograde Synaptic Vesicle Transport	Response To Zinc Ion Positive Regulation Of Transport Regulation Of Sequestering Of Zinc Ion Zinc Ion Transmembrane Transport Zinc Ion Import Into Synaptic Vesicle
Pathways		Golgi Associated Vesicle Biogenesis	Zinc efflux and compartmentalization by the SLC30 family
Drugs
Diseases
GWAS			Metabolite levels ( 23823483)
Interacting Genes		7 interacting genes: AP3B2 AP3D1 AP3S2 IRS1 RUFY1 SCARB2 SLC30A3	28 interacting genes: AP3B1 AP3D1 AP3S1 CD40 CGRRF1 DNAJC5 ELOVL4 FCRL3 GJA8 GOLM1 GPR152 GPR42 GPX8 HSD17B13 LMNA NAALADL2 OCIAD1 RETREG3 RNF19B RTN3 SCN3B SGPL1 SLC10A6 SLC30A8 SLC34A2 SLC35C2 TMEM14B TMEM242
Entrez ID		1176	7781
HPRD ID		03298	11924
Ensembl ID		ENSG00000177879	ENSG00000115194
Uniprot IDs		F5H459 Q92572	B4DXX8 Q99726
PDB IDs
Enriched GO Terms of Interacting Partners?
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