RAB11FIP1 and RAB4A

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		RAB11FIP1	RAB4A
Description		RAB11 family interacting protein 1	RAB4A, member RAS oncogene family
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GO Annotations	Cellular Component	Cytosol Phagocytic Vesicle Membrane Intracellular Membrane-bounded Organelle Recycling Endosome	Endosome Cytosol Plasma Membrane Cytoplasmic Vesicle Membrane Early Endosome Membrane Vesicle Insulin-responsive Compartment Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome Membrane Extracellular Exosome Postsynaptic Recycling Endosome Anchored Component Of Synaptic Vesicle Membrane
	Molecular Function		ATPase Activator Activity GTPase Activity Protein Binding GTP Binding GDP Binding Syntaxin Binding Ionotropic Glutamate Receptor Binding ATPase Binding
	Biological Process	Protein Transport Regulated Exocytosis Negative Regulation Of Adiponectin Secretion	Phosphatidylinositol Biosynthetic Process Protein Transport Antigen Processing And Presentation Regulation Of Endocytosis Rab Protein Signal Transduction Positive Regulation Of ATPase Activity
Pathways			Translocation of SLC2A4 (GLUT4) to the plasma membrane Synthesis of PIPs at the plasma membrane TBC/RABGAPs RAB geranylgeranylation MET receptor recycling
Drugs
Diseases
GWAS		Axial length ( 24144296)	Aging ( 22773346) Leukoderma in response to rhododendrol ( 32558222) Mean arterial pressure (alcohol consumption interaction) ( 24376456) Mercury levels ( 26025379) Response to antidepressants in depression ( 27622933)
Interacting Genes		5 interacting genes: RAB11A RAB11B RAB25 RAB4A RFFL	33 interacting genes: ACTB APBB3 CD2AP CDK1 CHM DYNC1LI1 DYNLL1 EXOC5 FAM71C GDI2 GRIPAP1 HACE1 IDH3A KCTD7 KIF3B MAPK3 PIN1 PRKCI PTTG1IP RAB11FIP1 RAB7A RABAC1 RABEP1 RABEP2 RABGAP1 RABGEF1 RBSN RUFY1 SOD2 STX4 TP53 VPS52 ZNF830
Entrez ID		80223	5867
HPRD ID		09787	01541
Ensembl ID		ENSG00000156675	ENSG00000168118
Uniprot IDs		Q6WKZ4	A0A024R3U9 A0A087WYT5 P20338
PDB IDs		4D0G	1YU9 1Z0K 2BMD 2BME
Enriched GO Terms of Interacting Partners?
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