TARS2 and PLIN3

Data Source:
BioGRID (two hybrid)

		TARS2	PLIN3
Description		threonyl-tRNA synthetase 2, mitochondrial	perilipin 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Mitochondrial Matrix	Cytoplasm Endosome Golgi Apparatus Lipid Droplet Cytosol Endosome Membrane Membrane Transport Vesicle
	Molecular Function	Aminoacyl-tRNA Editing Activity Threonine-tRNA Ligase Activity Protein Binding ATP Binding Protein Homodimerization Activity	Protein Binding Cadherin Binding
	Biological Process	Threonyl-tRNA Aminoacylation Mitochondrial Threonyl-tRNA Aminoacylation Aminoacyl-tRNA Metabolism Involved In Translational Fidelity	Positive Regulation Of Sequestering Of Triglyceride Vesicle-mediated Transport Lipid Storage
Pathways		Mitochondrial tRNA aminoacylation	Triglyceride catabolism Retrograde transport at the Trans-Golgi-Network Lipophagy Chaperone Mediated Autophagy Late endosomal microautophagy RHOBTB3 ATPase cycle
Drugs		Threonine	Idursulfase Galsulfase
Diseases
GWAS		Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Chronotype ( 30696823 27494321) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) LDL cholesterol levels ( 32203549) Morning person ( 30696823) Morning vs. evening chronotype ( 27494321) Plateletcrit ( 32888494) Refractive error ( 32231278) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Basal cell carcinoma ( 27539887) Lung cancer in ever smokers ( 28604730) Visceral fat ( 30942860)
Interacting Genes		9 interacting genes: ARL6IP1 ASB6 FKBP7 HOMEZ PLIN3 SLC17A9 SYPL1 TARS3 TNFRSF10D	32 interacting genes: ABHD4 ABHD5 APP CCNC CHMP4B CMTM5 CPD CYBC1 GAD2 HSD17B13 IGF2R LNPK M6PR MAX MIEF1 MYG1 PBX3 PIAS3 PTPN9 RAB9A SFT2D2 SMAD2 SNX1 SNX2 SPART SYNGR1 SYNGR3 SYP TARS2 TBC1D13 TBPL1 TMEM14C
Entrez ID		80222	10226
HPRD ID		18148	04080
Ensembl ID		ENSG00000143374	ENSG00000105355
Uniprot IDs		Q9BW92 U3KQG0	A0A140VJN8 O60664
PDB IDs
Enriched GO Terms of Interacting Partners?
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