RABEP2 and RAB4A

Data Source:
BioGRID (two hybrid)

		RABEP2	RAB4A
Description		rabaptin, RAB GTPase binding effector protein 2	RAB4A, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Early Endosome Centrosome Cytosol Ciliary Basal Body Intracellular Membrane-bounded Organelle	Endosome Cytosol Plasma Membrane Cytoplasmic Vesicle Membrane Early Endosome Membrane Vesicle Insulin-responsive Compartment Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome Membrane Extracellular Exosome Postsynaptic Recycling Endosome Anchored Component Of Synaptic Vesicle Membrane
	Molecular Function	GTPase Activator Activity Protein Binding Growth Factor Activity	ATPase Activator Activity GTPase Activity Protein Binding GTP Binding GDP Binding Syntaxin Binding Ionotropic Glutamate Receptor Binding ATPase Binding
	Biological Process	Endocytosis Signal Transduction Protein Transport Cell Projection Organization Positive Regulation Of GTPase Activity Regulation Of Cilium Assembly	Phosphatidylinositol Biosynthetic Process Protein Transport Antigen Processing And Presentation Regulation Of Endocytosis Rab Protein Signal Transduction Positive Regulation Of ATPase Activity
Pathways			Translocation of SLC2A4 (GLUT4) to the plasma membrane Synthesis of PIPs at the plasma membrane TBC/RABGAPs RAB geranylgeranylation MET receptor recycling
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 31453325) Body mass index variance ( 31453325) Brain morphology (MOSTest) ( 32665545) Cannabis use ( 30150663) Crohn's disease ( 28067908) Estimated glomerular filtration rate ( 31152163) Extremely high intelligence ( 29520040) HDL cholesterol levels ( 32203549) Household income (MTAG) ( 31844048) Inflammatory bowel disease ( 28067908 23128233) Obesity ( 23563607)	Aging ( 22773346) Leukoderma in response to rhododendrol ( 32558222) Mean arterial pressure (alcohol consumption interaction) ( 24376456) Mercury levels ( 26025379) Response to antidepressants in depression ( 27622933)
Interacting Genes		7 interacting genes: FBXO25 FRAT1 MAP3K1 RAB4A RAB5A UBC VPS52	33 interacting genes: ACTB APBB3 CD2AP CDK1 CHM DYNC1LI1 DYNLL1 EXOC5 FAM71C GDI2 GRIPAP1 HACE1 IDH3A KCTD7 KIF3B MAPK3 PIN1 PRKCI PTTG1IP RAB11FIP1 RAB7A RABAC1 RABEP1 RABEP2 RABGAP1 RABGEF1 RBSN RUFY1 SOD2 STX4 TP53 VPS52 ZNF830
Entrez ID		79874	5867
HPRD ID		17948	01541
Ensembl ID		ENSG00000177548	ENSG00000168118
Uniprot IDs		Q9H5N1	A0A024R3U9 A0A087WYT5 P20338
PDB IDs			1YU9 1Z0K 2BMD 2BME
Enriched GO Terms of Interacting Partners?
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