CPSF7 and SNX18

Data Source:
BioGRID (two hybrid)

		CPSF7	SNX18
Description		cleavage and polyadenylation specific factor 7	sorting nexin 18
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex MRNA Cleavage Factor Complex Membrane	Endosome Membrane Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Cytoplasmic Vesicle Extracellular Exosome
	Molecular Function	RNA Binding Protein Binding	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding
	Biological Process	MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription MRNA 3'-end Processing Protein Tetramerization Protein Heterotetramerization Pre-mRNA Cleavage Required For Polyadenylation MRNA Alternative Polyadenylation Messenger Ribonucleoprotein Complex Assembly	Mitotic Cytokinesis Endocytosis Protein Transport Endosomal Transport Cleavage Furrow Formation Positive Regulation Of GTPase Activity
Pathways		mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs	Clathrin-mediated endocytosis
Drugs
Diseases
GWAS			Immune response to smallpox vaccine (IL-6) ( 22542470)
Interacting Genes		59 interacting genes: APBB1 ARMC7 ATXN1 CATSPER1 CFAP206 CLK2 CSNK2A1 DVL2 EPM2AIP1 EWSR1 GAS8 GCC1 GRB2 GUCD1 HINT1 HNRNPF ITCH LENG8 LNX1 MIR1-1 MIR1-2 MIR10B MIR128-2 MIR141 MIR155 MIR16-1 MIR17 MIR18B MIR199A1 MIR19A MIR19B1 MIR25 MIR29C MIR34B MIR7-1 MIR9-2 MIR93 MIRLET7B NCK2 NUDT21 PATZ1 PID1 PRKAA2 PRMT2 RBM10 RUNX1T1 SEC23B SMAD3 SNRNP25 SNX18 SORBS3 SPG21 SRPK2 SUMO2 TLE5 TNS2 U2AF2 WBP4 WWOX	19 interacting genes: ABI2 CPSF7 CYSRT1 DPPA4 GABARAP GOLGA2 HSF2BP HSPB2 HSPB2-C11orf52 KHDRBS3 KRTAP1-1 KRTAP6-3 MAP1LC3B MDFI MSS51 PTPN21 SOS1 SOS2 ZBTB42
Entrez ID		79869	112574
HPRD ID		16906	15407
Ensembl ID		ENSG00000149532	ENSG00000178996
Uniprot IDs		B4DGF8 Q8N684	Q96RF0
PDB IDs		3N9U
Enriched GO Terms of Interacting Partners?
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