SNX18 and DPPA4

Data Source:
BioGRID (two hybrid)

		SNX18	DPPA4
Description		sorting nexin 18	developmental pluripotency associated 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endosome Membrane Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Cytoplasmic Vesicle Extracellular Exosome	Nucleus Nucleoplasm
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding	Chromatin Binding Protein Binding
	Biological Process	Mitotic Cytokinesis Endocytosis Protein Transport Endosomal Transport Cleavage Furrow Formation Positive Regulation Of GTPase Activity	Multicellular Organism Development Somatic Stem Cell Population Maintenance System Development
Pathways		Clathrin-mediated endocytosis	POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation
Drugs
Diseases
GWAS		Immune response to smallpox vaccine (IL-6) ( 22542470)	Cardiac hypertrophy ( 21348951) Corneal astigmatism ( 23761726) Metabolite levels ( 23823483)
Interacting Genes		19 interacting genes: ABI2 CPSF7 CYSRT1 DPPA4 GABARAP GOLGA2 HSF2BP HSPB2 HSPB2-C11orf52 KHDRBS3 KRTAP1-1 KRTAP6-3 MAP1LC3B MDFI MSS51 PTPN21 SOS1 SOS2 ZBTB42	35 interacting genes: BTBD2 CIR1 CRK DPPA2 EAF1 EIF4A2 EMD FOXR1 GMPPB GRAP GRB2 GTPBP3 HTT INO80B KAT14 LDOC1 MAGOH MAPK6 MISP NEDD9 OSTF1 PLEKHF2 PTPRO QARS1 RPGRIP1 RPS6KB1 SH3GL1 SH3GL2 SH3GL3 SNX18 SNX33 SPANXN2 TLK1 TNIP1 VIM
Entrez ID		112574	55211
HPRD ID		15407	16836
Ensembl ID		ENSG00000178996	ENSG00000121570
Uniprot IDs		Q96RF0	Q7L190
PDB IDs
Enriched GO Terms of Interacting Partners?
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