RBFA and DERL2

Data Source:
BioGRID (two hybrid)

		RBFA	DERL2
Description		ribosome binding factor A	derlin 2
Image			No pdb structure
GO Annotations	Cellular Component	Cellular_component Mitochondrion	Hrd1p Ubiquitin Ligase ERAD-L Complex Early Endosome Late Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Endoplasmic Reticulum Membrane Endoplasmic Reticulum Quality Control Compartment
	Molecular Function	Molecular_function Protein Binding	Signal Recognition Particle Binding Protein Binding Protein-containing Complex Binding Misfolded Protein Binding Ubiquitin-specific Protease Binding
	Biological Process	RRNA Processing Biological_process	Suckling Behavior Positive Regulation Of Cell Population Proliferation Viral Process Positive Regulation Of Cell Growth Ubiquitin-dependent ERAD Pathway Endoplasmic Reticulum Unfolded Protein Response Retrograde Protein Transport, ER To Cytosol Negative Regulation Of Retrograde Protein Transport, ER To Cytosol Endoplasmic Reticulum Mannose Trimming
Pathways			ABC-family proteins mediated transport Hedgehog ligand biogenesis Hh mutants are degraded by ERAD Defective CFTR causes cystic fibrosis ER Quality Control Compartment (ERQC)
Drugs
Diseases
GWAS			Asparaginase hypersensitivity in acute lymphoblastic leukemia ( 25987655)
Interacting Genes		22 interacting genes: ABHD5 AGTRAP ANK1 CACFD1 CAV3 CMTM5 CMTM6 DERL2 ERLIN1 FATE1 FKBP7 GPR152 GPX8 HIGD1C LEPROTL1 MDK PEX12 RHEX SMIM5 SYP SYPL1 YIF1A	12 interacting genes: DIABLO FXYD6 KRTAP10-3 KRTAP10-7 KRTAP10-8 LMNA MELTF MPP1 PTPN9 RBFA SERPINA1 SFT2D1
Entrez ID		79863	51009
HPRD ID		07959	16796
Ensembl ID		ENSG00000101546	ENSG00000072849
Uniprot IDs		Q8N0V3	I3L3R8 Q9GZP9
PDB IDs		2E7G
Enriched GO Terms of Interacting Partners?
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