DERL2 and MPP1

Data Source:
BioGRID (two hybrid)

		DERL2	MPP1
Description		derlin 2	membrane palmitoylated protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Hrd1p Ubiquitin Ligase ERAD-L Complex Early Endosome Late Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Endoplasmic Reticulum Membrane Endoplasmic Reticulum Quality Control Compartment	Plasma Membrane Membrane Cortical Cytoskeleton Stereocilium Centriolar Satellite
	Molecular Function	Signal Recognition Particle Binding Protein Binding Protein-containing Complex Binding Misfolded Protein Binding Ubiquitin-specific Protease Binding	Guanylate Kinase Activity Protein Binding
	Biological Process	Suckling Behavior Positive Regulation Of Cell Population Proliferation Viral Process Positive Regulation Of Cell Growth Ubiquitin-dependent ERAD Pathway Endoplasmic Reticulum Unfolded Protein Response Retrograde Protein Transport, ER To Cytosol Negative Regulation Of Retrograde Protein Transport, ER To Cytosol Endoplasmic Reticulum Mannose Trimming	Signal Transduction GMP Metabolic Process GDP Metabolic Process Regulation Of Neutrophil Chemotaxis
Pathways		ABC-family proteins mediated transport Hedgehog ligand biogenesis Hh mutants are degraded by ERAD Defective CFTR causes cystic fibrosis ER Quality Control Compartment (ERQC)
Drugs
Diseases
GWAS		Asparaginase hypersensitivity in acute lymphoblastic leukemia ( 25987655)	Hematology traits ( 23263863) Mean corpuscular volume ( 23263863) Red blood cell traits ( 23446634)
Interacting Genes		12 interacting genes: DIABLO FXYD6 KRTAP10-3 KRTAP10-7 KRTAP10-8 LMNA MELTF MPP1 PTPN9 RBFA SERPINA1 SFT2D1	43 interacting genes: ABCC4 ACER1 ACER2 AGPAT3 AMOTL2 AP2M1 APH1A ATP5F1C ATRAID BHLHB9 DERL2 DGAT2L6 DNPEP ERBIN GADD45A GSK3B GYPC HNRNPD INCA1 KLHL12 MAP3K20 MEOX2 NR1H2 OPTN PAQR8 PRIMPOL RPRM RPS6KA1 RPS6KA6 SGSM2 SLC35E1 SMN1 SRSF10 STK3 STUB1 SYNGR3 TK1 TMEM239 TRIM55 TRIM63 USP21 UXT ZNF639
Entrez ID		51009	4354
HPRD ID		16796	02370
Ensembl ID		ENSG00000072849	ENSG00000130830
Uniprot IDs		I3L3R8 Q9GZP9	B4E325 Q00013
PDB IDs			2EJY 2EV8 3NEY
Enriched GO Terms of Interacting Partners?
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