CSPP1 and UBR5

Data Source:
BioGRID (protein complementation assay)

		CSPP1	UBR5
Description		centrosome and spindle pole associated protein 1	ubiquitin protein ligase E3 component n-recognin 5
Image		No pdb structure
GO Annotations	Cellular Component	Spindle Pole Cytoplasm Centrosome Spindle Microtubule	Nucleus Nucleoplasm Cytosol Membrane Protein-containing Complex Perinuclear Region Of Cytoplasm
	Molecular Function		RNA Binding Protein Binding Zinc Ion Binding Ubiquitin-ubiquitin Ligase Activity Ubiquitin Binding Ubiquitin Protein Ligase Activity
	Biological Process	Positive Regulation Of Cytokinesis Positive Regulation Of Cell Division	Protein Polyubiquitination DNA Repair Cellular Response To DNA Damage Stimulus Positive Regulation Of Gene Expression Viral Process Positive Regulation Of Protein Import Into Nucleus Progesterone Receptor Signaling Pathway Protein K48-linked Ubiquitination Positive Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Histone H2A K63-linked Ubiquitination Regulation Of Double-strand Break Repair Negative Regulation Of Double-strand Break Repair
Pathways
Drugs
Diseases
GWAS		Hip circumference adjusted for BMI ( 28552196)	Chromosomal aberration frequency (total) ( 31586183) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Rate of cognitive decline in mild cognitive impairment (time interaction) ( 22833209) Type 2 diabetes (age of onset) ( 28060188)
Interacting Genes		7 interacting genes: GOLGA2 MRFAP1L1 PFDN5 RINT1 RPGRIP1 TRIM14 UBR5	30 interacting genes: BARD1 CIB1 CSPP1 DYRK2 ERG GSK3B KPNA1 KPNA2 KPNB1 MAPK1 MOAP1 NR1I2 OTUD5 PAIP1 PAIP2 PCK1 PGR SATB1 SMAD2 SOX2 TCEA1 TOPBP1 TXNIP UBC UBE2A UBE2B UBE2D2 UBE2D3 UBE2L3 ZNF207
Entrez ID		79848	51366
HPRD ID		07991	06436
Ensembl ID		ENSG00000104218	ENSG00000104517
Uniprot IDs		Q1MSJ5 Q9H688	O95071
PDB IDs			1I2T 2QHO 3PT3
Enriched GO Terms of Interacting Partners?
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