UBR5 and ZNF207

Data Source:
BioGRID (pull down)

		UBR5	ZNF207
Description		ubiquitin protein ligase E3 component n-recognin 5	zinc finger protein 207
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Membrane Protein-containing Complex Perinuclear Region Of Cytoplasm	Kinetochore Condensed Chromosome Kinetochore Nucleus Nucleoplasm Nucleolus Cytoplasm Spindle Microtubule Spindle Matrix
	Molecular Function	RNA Binding Protein Binding Zinc Ion Binding Ubiquitin-ubiquitin Ligase Activity Ubiquitin Binding Ubiquitin Protein Ligase Activity	DNA Binding RNA Binding Protein Binding Microtubule Binding Metal Ion Binding
	Biological Process	Protein Polyubiquitination DNA Repair Cellular Response To DNA Damage Stimulus Positive Regulation Of Gene Expression Viral Process Positive Regulation Of Protein Import Into Nucleus Progesterone Receptor Signaling Pathway Protein K48-linked Ubiquitination Positive Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Histone H2A K63-linked Ubiquitination Regulation Of Double-strand Break Repair Negative Regulation Of Double-strand Break Repair	Mitotic Sister Chromatid Segregation Microtubule Bundle Formation Mitotic Spindle Assembly Checkpoint Attachment Of Spindle Microtubules To Kinetochore Microtubule Polymerization Protein Stabilization Cell Division Regulation Of Chromosome Segregation Mitotic Spindle Assembly
Pathways
Drugs
Diseases
GWAS		Chromosomal aberration frequency (total) ( 31586183) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Rate of cognitive decline in mild cognitive impairment (time interaction) ( 22833209) Type 2 diabetes (age of onset) ( 28060188)	Survival in pancreatic cancer ( 28470677)
Interacting Genes		30 interacting genes: BARD1 CIB1 CSPP1 DYRK2 ERG GSK3B KPNA1 KPNA2 KPNB1 MAPK1 MOAP1 NR1I2 OTUD5 PAIP1 PAIP2 PCK1 PGR SATB1 SMAD2 SOX2 TCEA1 TOPBP1 TXNIP UBC UBE2A UBE2B UBE2D2 UBE2D3 UBE2L3 ZNF207	9 interacting genes: ERBB3 HNRNPM HNRNPUL1 MAP2K2 POLR1B TET2 UBR5 WBP4 WDR77
Entrez ID		51366	7756
HPRD ID		06436	04576
Ensembl ID		ENSG00000104517	ENSG00000010244
Uniprot IDs		O95071	O43670
PDB IDs		1I2T 2QHO 3PT3
Enriched GO Terms of Interacting Partners?
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