SNIP1 and PRPF3

Data Source:
BioGRID (two hybrid)

		SNIP1	PRPF3
Description		Smad nuclear interacting protein 1	pre-mRNA processing factor 3
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol U2-type Precatalytic Spliceosome	Nucleus Nucleoplasm Spliceosomal Complex Cytosol Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome
	Molecular Function	RNA Binding MRNA Binding Protein Binding	RNA Binding Protein Binding Identical Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Regulation Of Transcription By RNA Polymerase II I-kappaB Kinase/NF-kappaB Signaling Production Of MiRNAs Involved In Gene Silencing By MiRNA	Spliceosomal Tri-snRNP Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases			Retinitis pigmentosa (RP)
GWAS		Axial length ( 24144296) Eyebrow thickness ( 26926045)	Ambidextrousness ( 32989287) Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Chronotype ( 27494321) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Low density lipoprotein cholesterol levels ( 30498476) Morning person ( 30696823) Morning vs. evening chronotype ( 27494321) Platelet count ( 32888494 27863252) Plateletcrit ( 27863252) Refractive error ( 32231278) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) White blood cell count ( 32888494)
Interacting Genes		49 interacting genes: CDK6 CLK2 CLK3 CREBBP DVL2 DVL3 EIF3C EP300 ESRRG FAF1 GMEB1 GYS1 HIPK1 HIPK3 KRTAP10-6 MAX MYC PHF19 PIAS1 PIAS2 PIAS3 PIAS4 POU2F1 PRPF3 PRPF40A RELA SETDB1 SF3B1 SMAD1 SMAD2 SMAD4 SON SP100 SPANXN2 SRPK2 SRRM4 STK3 TDG TNIP1 TOPORS TSPYL2 TTC14 UBE2I ZBTB9 ZCCHC10 ZCCHC7 ZMYM2 ZMYM5 ZNF451	52 interacting genes: BRCA1 CARD10 CASK CCDC125 CCDC136 CCDC85B CDC5L CEP70 CTNNBL1 DPY30 DVL2 DVL3 FAM9B FCHO1 FRA10AC1 GOLGA2 GPRASP2 GTPBP3 HSF2BP LZTS1 MAPRE1 MID2 NACC1 NAV2 NINL NKAP NKAPD1 OSBPL3 PCBP1 PHC2 PIP4K2B PRPF31 PSMD3 RABEP1 RBM39 RNF151 SART3 SHKBP1 SNIP1 SNRNP200 SSX2IP TRIM39 TSPYL1 TXLNA U2AF2 USP4 WBP4 ZBTB8A ZCCHC10 ZFPM2 ZGPAT ZRANB1
Entrez ID		79753	9129
HPRD ID		06999	07389
Ensembl ID		ENSG00000163877	ENSG00000117360
Uniprot IDs		B1AK66 Q8TAD8	O43395
PDB IDs		5Z56 5Z57 5Z58 6FF7	1X4Q 3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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