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ZYG11B and CUL2
Data Source:
HPRD
(in vivo)
ZYG11B
CUL2
Description
zyg-11 family member B, cell cycle regulator
cullin 2
Image
No pdb structure
GO Annotations
Cellular Component
Cul2-RING Ubiquitin Ligase Complex
Nucleoplasm
Cytosol
SCF Ubiquitin Ligase Complex
VCB Complex
Cullin-RING Ubiquitin Ligase Complex
Cul2-RING Ubiquitin Ligase Complex
Molecular Function
Protein Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Ubiquitin Protein Ligase Binding
Protein-containing Complex Binding
Biological Process
Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
G1/S Transition Of Mitotic Cell Cycle
Viral Process
Protein Ubiquitination
SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Post-translational Protein Modification
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Intrinsic Apoptotic Signaling Pathway
Pathways
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
Neddylation
Regulation of expression of SLITs and ROBOs
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Monocyte percentage of white cells (
32888494
)
Crohn's disease (
28067908
)
Inflammatory bowel disease (
28067908
)
Interacting Genes
4 interacting genes:
CUL2
ELOB
ELOC
GBF1
25 interacting genes:
ARID1B
CAND1
CDC34
COMMD1
COPS5
DCUN1D2
DCUN1D3
DCUN1D4
DCUN1D5
E2F1
ELOC
GPS1
KAT2A
KHNYN
MKNK2
NEDD8
RBX1
RNF7
SAP130
SENP8
UBC
UBE2D1
VHL
ZER1
ZYG11B
Entrez ID
79699
8453
HPRD ID
13356
06786
Ensembl ID
ENSG00000162378
ENSG00000108094
Uniprot IDs
A8DPD7
B4DK95
Q9C0D3
A0A0A0MTN0
A0A140VKB1
B7Z1Y1
Q13617
PDB IDs
4WQO
5N4W
6R6H
6R7F
6R7H
6R7I
6R7N
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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