SAP30L and GALNT10

Data Source:
BioGRID (enzymatic study, affinity chromatography technology)

		SAP30L	GALNT10
Description		SAP30 like	polypeptide N-acetylgalactosaminyltransferase 10
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GO Annotations	Cellular Component	Histone Deacetylase Complex Fibrillar Center Nucleoplasm Nucleolus	Golgi Membrane Golgi Apparatus Integral Component Of Membrane
	Molecular Function	DNA Binding Transcription Coregulator Activity Protein Binding Zinc Ion Binding Phosphatidylinositol-5-phosphate Binding Nucleosome Binding Histone Binding Non-sequence-specific DNA Binding, Bending	Polypeptide N-acetylgalactosaminyltransferase Activity Carbohydrate Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription, DNA-templated	Protein O-linked Glycosylation O-glycan Processing Protein Phosphopantetheinylation
Pathways		HDACs deacetylate histones NoRC negatively regulates rRNA expression Potential therapeutics for SARS	O-linked glycosylation of mucins
Drugs
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033) Angiotensin-converting enzyme inhibitor intolerance ( 28030426) QRS duration ( 25035420)	Autism spectrum disorder or schizophrenia ( 28540026) Behavioural disinhibition (generation interaction) ( 23942779) BMI (adjusted for smoking behaviour) ( 28443625) Body mass index ( 21701570 25673413 23583978) Body mass index (adult) ( 28430825) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Carotid artery intima media thickness (sex interaction) ( 25898001) Childhood body mass index ( 26604143) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Feeling tense ( 29500382) Menarche (age at onset) ( 25231870) Neurociticism ( 29500382) Neurofibrillary tangles ( 31497858) Response to quetiapine in schizophrenia ( 29503163) Schizophrenia ( 28991256 25056061 29483656 30285260) Triglyceride levels ( 32203549)
Interacting Genes		4 interacting genes: DVL3 FEZ1 FEZ2 HMBOX1	3 interacting genes: CNOT2 MUC1 MUC7
Entrez ID		79685	55568
HPRD ID		08563	12157
Ensembl ID		ENSG00000164576	ENSG00000164574
Uniprot IDs		Q9HAJ7	Q86SR1
PDB IDs		2N1U	2D7I 2D7R
Enriched GO Terms of Interacting Partners?
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