AIMP2 and FUBP1

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		AIMP2	FUBP1
Description		aminoacyl tRNA synthetase complex interacting multifunctional protein 2	far upstream element binding protein 1
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GO Annotations	Cellular Component	Nucleus Cytosol Membrane Aminoacyl-tRNA Synthetase Multienzyme Complex	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Protein Binding Molecular Adaptor Activity	Single-stranded DNA Binding RNA Binding MRNA Binding Protein Binding
	Biological Process	TRNA Aminoacylation For Protein Translation Apoptotic Process Negative Regulation Of Cell Population Proliferation Positive Regulation Of Protein Ubiquitination Type II Pneumocyte Differentiation Protein-containing Complex Assembly Positive Regulation Of Neuron Death Positive Regulation Of Aminoacyl-tRNA Ligase Activity	Regulation Of Gene Expression Positive Regulation Of Gene Expression
Pathways		Selenoamino acid metabolism Cytosolic tRNA aminoacylation
Drugs			Irofulven Sacituzumab govitecan
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494 27863252)	BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 25673413) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Lung cancer in never smokers ( 28604730) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Psoriasis ( 28537254)
Interacting Genes		104 interacting genes: ACTB AIMP1 APP BCAS2 BEX3 BLOC1S4 BRME1 BYSL C1orf216 CBY2 CCDC153 CEP126 CHD3 DARS1 DARS2 DEAF1 DISC1 DSN1 EPRS1 EPS8 EXOC8 FGB FHL3 FUBP1 GYS1 HSPA1A ICE1 KARS1 KDR KLC2 KRT31 KRT33B KRT34 KRT36 LMO2 LMO3 LNX1 LUC7L2 MATR3 MCF2L MIR106A MIR107 MIR122 MIR128-1 MIR128-2 MIR138-2 MIR15A MIR18A MIR199A1 MIR19A MIR19B1 MIR19B2 MIR200C MIR205 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR34A MIR34B MIR34C MIR429 MIR451A MIR7-1 MIR7-2 MIR92A2 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7I MIS18A NDEL1 NECAB2 NTAQ1 PFDN6 PLEKHF2 PPP2R1A PRKAA2 PRKN PSME1 RABEP1 SBK3 SIAH1 SLU7 SMURF2 SPATA18 TANK TCP11 TERF2IP TEX12 TFIP11 TRAF2 TRMT2A ZC3H12A ZGPAT	25 interacting genes: AIMP2 ANXA11 CCNH CELF1 CHD3 CRMP1 ESR1 GTF2H1 IMMT MAPK1IP1L MYOC PRPF40B PRR13 PUF60 SIRPA SMN1 SMURF2 SNRPA SNRPB SNRPC TIAL1 TLE1 U2AF2 VIM VPS37C
Entrez ID		7965	8880
HPRD ID		02915	10349
Ensembl ID		ENSG00000106305	ENSG00000162613
Uniprot IDs		A0A024QZY1 A8MU58 Q13155	A0A384MDX9 B4DT31 Q96AE4
PDB IDs		4DPG 4YCU 4YCW 5A1N 5A34 5A5H 5Y6L 6ILD 6IY6 6JPV 6K39	1J4W 2KXH 4LIJ 6Y24 6Y2C 6Y2D
Enriched GO Terms of Interacting Partners?
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