AIMP2 and KRT36

Data Source:
BioGRID (two hybrid)

		AIMP2	KRT36
Description		aminoacyl tRNA synthetase complex interacting multifunctional protein 2	keratin 36
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Membrane Aminoacyl-tRNA Synthetase Multienzyme Complex	Cytosol Intermediate Filament Extracellular Exosome
	Molecular Function	Protein Binding Molecular Adaptor Activity	Structural Constituent Of Skin Epidermis
	Biological Process	TRNA Aminoacylation For Protein Translation Apoptotic Process Negative Regulation Of Cell Population Proliferation Positive Regulation Of Protein Ubiquitination Type II Pneumocyte Differentiation Protein-containing Complex Assembly Positive Regulation Of Neuron Death Positive Regulation Of Aminoacyl-tRNA Ligase Activity	Biological_process Keratinization Regulation Of Keratinocyte Differentiation Cornification
Pathways		Selenoamino acid metabolism Cytosolic tRNA aminoacylation	Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494 27863252)
Interacting Genes		104 interacting genes: ACTB AIMP1 APP BCAS2 BEX3 BLOC1S4 BRME1 BYSL C1orf216 CBY2 CCDC153 CEP126 CHD3 DARS1 DARS2 DEAF1 DISC1 DSN1 EPRS1 EPS8 EXOC8 FGB FHL3 FUBP1 GYS1 HSPA1A ICE1 KARS1 KDR KLC2 KRT31 KRT33B KRT34 KRT36 LMO2 LMO3 LNX1 LUC7L2 MATR3 MCF2L MIR106A MIR107 MIR122 MIR128-1 MIR128-2 MIR138-2 MIR15A MIR18A MIR199A1 MIR19A MIR19B1 MIR19B2 MIR200C MIR205 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR34A MIR34B MIR34C MIR429 MIR451A MIR7-1 MIR7-2 MIR92A2 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7I MIS18A NDEL1 NECAB2 NTAQ1 PFDN6 PLEKHF2 PPP2R1A PRKAA2 PRKN PSME1 RABEP1 SBK3 SIAH1 SLU7 SMURF2 SPATA18 TANK TCP11 TERF2IP TEX12 TFIP11 TRAF2 TRMT2A ZC3H12A ZGPAT	52 interacting genes: ABI2 ABI3 AIMP2 AMOT APP BCAS2 C1orf216 CCBE1 CCHCR1 CDC23 DMRT3 EXOC8 GEM GPS2 HCK HGS HOXC8 KRT1 KRT2 KRT3 KRT4 KRT6A KRT6C KRT73 KRT75 KRT76 KRT77 KRT78 KRT79 KRT8 KRT80 KRT85 KRT86 MAP3K1 MYOZ1 MYOZ3 PKN1 PLEKHN1 PPP1R18 PSMB1 QARS1 RESF1 RIBC1 SMURF1 TMSB4X TRAF4 TSGA10IP TTC23 TTLL10 TXLNA ZNF414 ZNF785
Entrez ID		7965	8689
HPRD ID		02915	05174
Ensembl ID		ENSG00000106305	ENSG00000126337
Uniprot IDs		A0A024QZY1 A8MU58 Q13155	O76013
PDB IDs		4DPG 4YCU 4YCW 5A1N 5A34 5A5H 5Y6L 6ILD 6IY6 6JPV 6K39
Enriched GO Terms of Interacting Partners?
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