GALNT14 and MUC5AC

Data Source:
BioGRID (enzymatic study)

		GALNT14	MUC5AC
Description		polypeptide N-acetylgalactosaminyltransferase 14	mucin 5AC, oligomeric mucus/gel-forming
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Integral Component Of Membrane	Extracellular Space Cytoplasm Golgi Lumen Plasma Membrane Extracellular Matrix Extracellular Exosome Mucus Layer
	Molecular Function	Polypeptide N-acetylgalactosaminyltransferase Activity Carbohydrate Binding Metal Ion Binding	Extracellular Matrix Structural Constituent
	Biological Process	O-glycan Processing Protein Phosphopantetheinylation	Stimulatory C-type Lectin Receptor Signaling Pathway O-glycan Processing Phosphatidylinositol-mediated Signaling
Pathways		O-linked glycosylation of mucins	Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) Dectin-2 family O-linked glycosylation of mucins Termination of O-glycan biosynthesis
Drugs
Diseases
GWAS		Eye movement (horizontal position gain) ( 30120336) HIV-1 viral setpoint ( 22174851) Levodopa-induced dyskinesia in levodopa treated Parkinson's disease ( 32733355) Oropharynx cancer ( 32276964) Type 2 diabetes ( 25102180)	Asthma ( 31959851) Asthma (adult onset) ( 31036433) Asthma (moderate or severe) ( 30552067) Idiopathic pulmonary fibrosis ( 24429156)
Interacting Genes		4 interacting genes: MUC13 MUC2 MUC5AC MUC7	2 interacting genes: GALNT12 GALNT14
Entrez ID		79623	4586
HPRD ID		12194
Ensembl ID		ENSG00000158089	ENSG00000215182
Uniprot IDs		B7Z5C5 Q96FL9	P98088
PDB IDs			5AJN 5AJO 5AJP
Enriched GO Terms of Interacting Partners?
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