MUC5AC and GALNT14

Data Source:
BioGRID (enzymatic study)

		MUC5AC	GALNT14
Description		mucin 5AC, oligomeric mucus/gel-forming	polypeptide N-acetylgalactosaminyltransferase 14
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Golgi Lumen Plasma Membrane Extracellular Matrix Extracellular Exosome Mucus Layer	Golgi Membrane Golgi Apparatus Integral Component Of Membrane
	Molecular Function	Extracellular Matrix Structural Constituent	Polypeptide N-acetylgalactosaminyltransferase Activity Carbohydrate Binding Metal Ion Binding
	Biological Process	Stimulatory C-type Lectin Receptor Signaling Pathway O-glycan Processing Phosphatidylinositol-mediated Signaling	O-glycan Processing Protein Phosphopantetheinylation
Pathways		Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) Dectin-2 family O-linked glycosylation of mucins Termination of O-glycan biosynthesis	O-linked glycosylation of mucins
Drugs
Diseases
GWAS		Asthma ( 31959851) Asthma (adult onset) ( 31036433) Asthma (moderate or severe) ( 30552067) Idiopathic pulmonary fibrosis ( 24429156)	Eye movement (horizontal position gain) ( 30120336) HIV-1 viral setpoint ( 22174851) Levodopa-induced dyskinesia in levodopa treated Parkinson's disease ( 32733355) Oropharynx cancer ( 32276964) Type 2 diabetes ( 25102180)
Interacting Genes		2 interacting genes: GALNT12 GALNT14	4 interacting genes: MUC13 MUC2 MUC5AC MUC7
Entrez ID		4586	79623
HPRD ID			12194
Ensembl ID		ENSG00000215182	ENSG00000158089
Uniprot IDs		P98088	B7Z5C5 Q96FL9
PDB IDs		5AJN 5AJO 5AJP
Enriched GO Terms of Interacting Partners?
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