NOL12 and SAP18

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NOL12	SAP18
Description		nucleolar protein 12	Sin3A associated protein 18
Image		No pdb structure
GO Annotations	Cellular Component	Nucleolus	Histone Deacetylase Complex Nucleus Nucleoplasm Cytosol Nuclear Body Nuclear Speck Exon-exon Junction Complex ASAP Complex
	Molecular Function	RNA Binding Protein Binding RRNA Binding Identical Protein Binding	Transcription Corepressor Activity RNA Binding Protein Binding Transcription Factor Binding
	Biological Process		Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Transcription By RNA Polymerase II MRNA Processing RNA Splicing Positive Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of MRNA Splicing, Via Spliceosome
Pathways		Major pathway of rRNA processing in the nucleolus and cytosol	HDACs deacetylate histones NoRC negatively regulates rRNA expression Potential therapeutics for SARS
Drugs
Diseases
GWAS		Basophil count ( 32888494) Brain morphology (MOSTest) ( 32665545) Pulse pressure ( 30224653)
Interacting Genes		19 interacting genes: APP BEND7 CDCA7L CDK4 CEP70 DVL2 DVL3 KIAA1191 KRTAP10-6 KRTAP10-7 MCC SAP18 SF3B3 SLC25A38 SOD2 SPANXN2 SSX2IP TERF1 TSPYL2	15 interacting genes: DEF6 ERBB3 HDAC1 IKZF1 INCA1 NOL12 NTAQ1 POLE2 RBM39 RNPS1 RPS3A SIN3A SUFU TADA3 TSC22D2
Entrez ID		79159	10284
HPRD ID		17537	04256
Ensembl ID		ENSG00000273899	ENSG00000150459
Uniprot IDs		A0A024R1M6 Q9UGY1	O00422
PDB IDs			2HDE
Enriched GO Terms of Interacting Partners?
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