C1orf50 and EIF2B1

Data Source:
BioGRID (two hybrid)

		C1orf50	EIF2B1
Description		chromosome 1 open reading frame 50	eukaryotic translation initiation factor 2B subunit alpha
Image		No pdb structure
GO Annotations	Cellular Component		Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 2B Complex Plasma Membrane Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Translation Initiation Factor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding Identical Protein Binding
	Biological Process		Translational Initiation Regulation Of Translational Initiation Response To Heat Response To Glucose Oligodendrocyte Development Response To Peptide Hormone Regulation Of Catalytic Activity T Cell Receptor Signaling Pathway
Pathways			Recycling of eIF2:GDP
Drugs
Diseases			Leukoencephalopathy with vanishing white matter; Vanishing white matter disease; Childhood ataxia with diffuse central nervous system hypomyelination (CACH); Cree leukoencephalopathy (CLE)
GWAS			Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		13 interacting genes: ADCY4 AHCY APPBP2 CRX EIF2B1 EPM2AIP1 INCA1 LRP2BP MEOX1 MEOX2 NTAQ1 REL TCF4	21 interacting genes: ADRA2A ADRA2B ADRA2C ADRB2 ARL4D ATF5 BZW2 C1orf50 CREBBP EIF2B2 EIF2S1 EIF2S2 EPM2A GORASP2 MED29 MRPL4 NTAQ1 RD3 TRIM59 TRIML2 UBE2I
Entrez ID		79078	1967
HPRD ID		14714	09458
Ensembl ID		ENSG00000164008	ENSG00000111361
Uniprot IDs		Q9BV19	Q14232
PDB IDs			3ECS 6CAJ 6EZO 6K71 6K72 6O81 6O85 6O9Z
Enriched GO Terms of Interacting Partners?
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