KXD1 and EXOC5

Data Source:
BioGRID (two hybrid)

		KXD1	EXOC5
Description		KxDL motif containing 1	exocyst complex component 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane BLOC-1 Complex BORC Complex	Exocyst Cytoplasm Cytosol Midbody
	Molecular Function	Protein Binding	Protein Binding Small GTPase Binding
	Biological Process	Vesicle-mediated Transport Lysosome Localization	Exocytosis Post-Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Protein Transport
Pathways			Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS			Alcohol consumption ( 23743675) Chronotype ( 30696823) Response to ranibizumab in age-related macular degeneration (exudative) ( 30054556)
Interacting Genes		44 interacting genes: APPL1 ARHGDIG BORCS6 C4orf46 CCDC185 CCDC33 CEP170P1 CEP19 CEP63 DYRK2 ELOA ELOA2 EWSR1 EXOC5 EXOC7 FXR2 GABARAPL1 HAUS1 IFT20 ING5 ITSN2 KRT81 LMO3 LNX1 LRRC45 MAB21L3 MAP1LC3A MAP1LC3B MCRS1 MOB1A MYH7 NIF3L1 NUDT18 RABGEF1 RNF183 RPL9 STX11 TCEA2 TPM1 TPM3 UTP6 ZBTB25 ZC4H2 ZNF417	43 interacting genes: ACTR3B ADCK1 ARF6 BARD1 BRMS1L C1orf216 CCDC102B CDH2 CRYBB1 DEUP1 DNAAF4 EDRF1 ENO2 EXOC6 EXOC6B FGA FRMD6 HDDC3 HGS ICA1 IFT57 KIFC3 KXD1 MAGEA3 MAGEA6 OAS1 PRKCG PSTPIP1 PTK6 PYCARD RAB14 RAB4A RAB4B RALA SOX10 SPACA9 TBX21 THOC1 TNPO2 TTC23L TXLNB TXNL4A USP2
Entrez ID		79036	10640
HPRD ID		14526	07258
Ensembl ID		ENSG00000105700	ENSG00000070367
Uniprot IDs		A0A024R7M2 Q9BQD3	O00471
PDB IDs
Enriched GO Terms of Interacting Partners?
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