KCNAB1 and SLC39A1

Data Source:
HPRD (two hybrid)

		KCNAB1	SLC39A1
Description		potassium voltage-gated channel subfamily A member regulatory beta subunit 1	solute carrier family 39 member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Voltage-gated Potassium Channel Complex Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Dendrite Cytoplasm Potassium Channel Complex Perikaryon Juxtaparanode Region Of Axon Proximal Dendrite	Endoplasmic Reticulum Membrane Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Aldo-keto Reductase (NADP) Activity Voltage-gated Potassium Channel Activity Potassium Channel Regulator Activity Protein Domain Specific Binding Ion Channel Binding NADPH Binding	Signaling Receptor Binding Zinc Ion Transmembrane Transporter Activity Protein Binding Inorganic Cation Transmembrane Transporter Activity
	Biological Process	Potassium Ion Transport Brain Development Heart Development Skeletal Muscle Tissue Development Myoblast Differentiation Diaphragm Development Potassium Ion Transmembrane Transport Regulation Of Potassium Ion Transmembrane Transport Regulation Of Delayed Rectifier Potassium Channel Activity Negative Regulation Of Delayed Rectifier Potassium Channel Activity Negative Regulation Of Voltage-gated Potassium Channel Activity	In Utero Embryonic Development Cation Transport Embryonic Cranial Skeleton Morphogenesis Limb Development Zinc Ion Transmembrane Transport
Pathways		Voltage gated Potassium channels	Zinc influx into cells by the SLC39 gene family
Drugs		Enflurane Promethazine Miconazole
Diseases
GWAS		Age-related nuclear cataracts ( 24951543) Aging traits ( 17903295) Coronary artery disease ( 26708285) Focal epilepsy (with hippocampal sclerosis) ( 30531953) Offspring birth weight ( 31043758)	Age at first birth ( 27798627) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cooked vegetable consumption ( 32066663) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Empathy quotient ( 29527006) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) Lentiform nucleus volume ( 22903471) Raw vegetable consumption ( 32066663) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		9 interacting genes: APP DLG1 FBXO7 KCNA2 NEDD4 NEDD4L SLC39A1 SLC39A2 SRPK1	16 interacting genes: CERS2 COMT CXCL16 CXCL9 CYB561 HTR2C HTR4 KCNAB1 KCNAB2 NOTCH3 PLEKHM2 PRKCZ SHB SLC39A2 TRARG1 YIPF6
Entrez ID		7881	27173
HPRD ID		03089	11984
Ensembl ID		ENSG00000169282	ENSG00000143570
Uniprot IDs		B7Z435 B7Z8E5 F8W6W4 Q14722 Q5MJQ3	A0A0A0MTL8 Q9NY26
PDB IDs
Enriched GO Terms of Interacting Partners?
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