KCNAB1 and SLC39A2

Data Source:
HPRD (two hybrid)

		KCNAB1	SLC39A2
Description		potassium voltage-gated channel subfamily A member regulatory beta subunit 1	solute carrier family 39 member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Voltage-gated Potassium Channel Complex Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Dendrite Cytoplasm Potassium Channel Complex Perikaryon Juxtaparanode Region Of Axon Proximal Dendrite	Plasma Membrane Integral Component Of Plasma Membrane Membrane Cytoplasmic Vesicle Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	Aldo-keto Reductase (NADP) Activity Voltage-gated Potassium Channel Activity Potassium Channel Regulator Activity Protein Domain Specific Binding Ion Channel Binding NADPH Binding	Zinc Ion Transmembrane Transporter Activity Protein Binding
	Biological Process	Potassium Ion Transport Brain Development Heart Development Skeletal Muscle Tissue Development Myoblast Differentiation Diaphragm Development Potassium Ion Transmembrane Transport Regulation Of Potassium Ion Transmembrane Transport Regulation Of Delayed Rectifier Potassium Channel Activity Negative Regulation Of Delayed Rectifier Potassium Channel Activity Negative Regulation Of Voltage-gated Potassium Channel Activity	Zinc Ion Transport Zinc Ion Transmembrane Transport
Pathways		Voltage gated Potassium channels	Zinc influx into cells by the SLC39 gene family
Drugs		Enflurane Promethazine Miconazole
Diseases
GWAS		Age-related nuclear cataracts ( 24951543) Aging traits ( 17903295) Coronary artery disease ( 26708285) Focal epilepsy (with hippocampal sclerosis) ( 30531953) Offspring birth weight ( 31043758)
Interacting Genes		9 interacting genes: APP DLG1 FBXO7 KCNA2 NEDD4 NEDD4L SLC39A1 SLC39A2 SRPK1	51 interacting genes: AQP1 AQP6 ARL13B BCL2L2 BTN2A2 C3orf52 C4orf3 CD79A CLCA4 CNR2 COL4A5 COMT CREB3L1 CXCR2 CYB561 EHHADH EMC6 FCER1G FXYD3 FXYD6 GJA8 GPR152 GPR42 KCNAB1 KCNAB2 LY6G6C MFSD6 MS4A13 PLN PNLIPRP1 SEC22A SLC18A1 SLC30A2 SLC30A8 SLC39A1 SLC39A9 SLC66A1 SLC7A1 SSMEM1 ST6GAL2 STATH TMEM107 TMEM14B TMEM229B TMEM237 TMEM54 TMEM60 TMEM86A TRHR UPK1B YIPF6
Entrez ID		7881	29986
HPRD ID		03089	15385
Ensembl ID		ENSG00000169282	ENSG00000165794
Uniprot IDs		B7Z435 B7Z8E5 F8W6W4 Q14722 Q5MJQ3	Q9NP94
PDB IDs
Enriched GO Terms of Interacting Partners?
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