SLC39A1 and KCNAB2

Data Source:
HPRD (two hybrid)

		SLC39A1	KCNAB2
Description		solute carrier family 39 member 1	potassium voltage-gated channel subfamily A regulatory beta subunit 2
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Plasma Membrane Membrane Integral Component Of Membrane	Cytosol Microtubule Plasma Membrane Voltage-gated Potassium Channel Complex Membrane Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Specific Granule Membrane Juxtaparanode Region Of Axon Synapse Tertiary Granule Membrane Pinceau Fiber
	Molecular Function	Signaling Receptor Binding Zinc Ion Transmembrane Transporter Activity Protein Binding Inorganic Cation Transmembrane Transporter Activity	Aldo-keto Reductase (NADP) Activity Voltage-gated Potassium Channel Activity Protein Binding Potassium Channel Regulator Activity Ion Channel Binding
	Biological Process	In Utero Embryonic Development Cation Transport Embryonic Cranial Skeleton Morphogenesis Limb Development Zinc Ion Transmembrane Transport	Neutrophil Degranulation NADPH Oxidation Potassium Ion Transmembrane Transport Regulation Of Action Potential Regulation Of Potassium Ion Transmembrane Transport Regulation Of Protein Localization To Cell Surface
Pathways		Zinc influx into cells by the SLC39 gene family	Voltage gated Potassium channels Neutrophil degranulation
Drugs			Enflurane Promethazine Miconazole
Diseases
GWAS		Age at first birth ( 27798627) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cooked vegetable consumption ( 32066663) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Empathy quotient ( 29527006) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) Lentiform nucleus volume ( 22903471) Raw vegetable consumption ( 32066663) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Metabolite levels ( 23823483)
Interacting Genes		16 interacting genes: CERS2 COMT CXCL16 CXCL9 CYB561 HTR2C HTR4 KCNAB1 KCNAB2 NOTCH3 PLEKHM2 PRKCZ SHB SLC39A2 TRARG1 YIPF6	8 interacting genes: ATXN1 CD4 KCNA2 NEDD4 NEDD4L SLC39A1 SLC39A2 SQSTM1
Entrez ID		27173	8514
HPRD ID		11984	03090
Ensembl ID		ENSG00000143570	ENSG00000069424
Uniprot IDs		A0A0A0MTL8 Q9NY26	A1PR14 B2R776 Q13303
PDB IDs			1ZSX
Enriched GO Terms of Interacting Partners?
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