BSND and COL8A2

Data Source:
BioGRID (two hybrid)

		BSND	COL8A2
Description		barttin CLCNK type accessory subunit beta	collagen type VIII alpha 2 chain
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane Protein-containing Complex	Extracellular Region Collagen Trimer Basement Membrane Extracellular Space Endoplasmic Reticulum Lumen Extracellular Matrix Collagen-containing Extracellular Matrix
	Molecular Function	Chloride Channel Activity Protein Binding Chloride Channel Regulator Activity	Extracellular Matrix Structural Constituent Extracellular Matrix Structural Constituent Conferring Tensile Strength Protein-macromolecule Adaptor Activity
	Biological Process	Chloride Transport Ion Transmembrane Transport Chloride Transmembrane Transport	Angiogenesis Extracellular Matrix Organization Camera-type Eye Morphogenesis Epithelial Cell Proliferation Cell-cell Adhesion
Pathways		Stimuli-sensing channels	Collagen degradation Collagen degradation Collagen biosynthesis and modifying enzymes Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions Collagen chain trimerization
Drugs
Diseases		Bartter syndrome	Posterior polymorphous corneal dystrophy (PPCD) Fuchs corneal dystrophy (FECD); Fuchs endothelial corneal dystrophy
GWAS		Allergic rhinitis ( 25085501) Carotid intima media thickness x smoking interaction ( 32117412) Coronary artery disease ( 32469254 33020668) Medication use (HMG CoA reductase inhibitors) ( 31015401) Mitochondrial DNA copy number ( 30704525)	Central corneal thickness ( 32528159 29760442) Corneal structure ( 23291589) Early spontaneous preterm birth ( 31194736) Intraocular pressure ( 29617998 29785010 31959993)
Interacting Genes		28 interacting genes: ADIPOQ APOL2 APP ARFIP1 BMP10 CDIPT CERT1 COL4A5 COL8A2 CSGALNACT2 CTSA ECPAS FATE1 GAD2 IGFBP5 JAGN1 MYG1 PBX3 PLSCR2 PTPN9 SLC30A8 SPG21 STX8 TBRG4 THAP4 TMEM60 VAMP3 ZFPL1	18 interacting genes: ARL13B ATP6V0E1 BSND COL8A1 CREB3L1 CYB5R3 DARS2 FAM209A FNDC9 GPR152 GPX8 LMNA MUC1 PEX12 PLEKHO1 SGTA TFAM TMX2
Entrez ID		7809	1296
HPRD ID		05914	08347
Ensembl ID		ENSG00000162399	ENSG00000171812
Uniprot IDs		Q5VU50 Q8WZ55	E9PP49 P25067
PDB IDs
Enriched GO Terms of Interacting Partners?
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