ZNF131 and KPNA6

Data Source:
BioGRID (pull down)

		ZNF131	KPNA6
Description		zinc finger protein 131	karyopherin subunit alpha 6
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Intermediate Filament Cytoskeleton	Nucleus Nucleoplasm Cytoplasm Membrane Host Cell
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Metal Ion Binding	Protein Binding Nuclear Localization Sequence Binding Nuclear Import Signal Receptor Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II	NLS-bearing Protein Import Into Nucleus Viral Genome Replication Mitigation Of Host Defenses By Symbiont Positive Regulation Of Transcription By RNA Polymerase II Maternal Process Involved In Female Pregnancy Entry Of Viral Genome Into Host Nucleus Through Nuclear Pore Complex Via Importin Positive Regulation Of Cytokine Production Involved In Inflammatory Response Positive Regulation Of Viral Life Cycle
Pathways		SUMOylation of transcription cofactors
Drugs
Diseases
GWAS		Body mass index ( 25673413) Mean corpuscular hemoglobin concentration ( 32888494) Menarche (age at onset) ( 25231870)	Body mass index ( 26426971)
Interacting Genes		9 interacting genes: EMSY FHL2 FHL5 HSPB1 KPNA2 KPNA3 KPNA6 MORN4 PIP4K2B	37 interacting genes: ANKRD11 ANP32A ANP32B ARNT BRCA1 CDKN1B CREBBP CSE1L DCPS EPAS1 FAM90A1 FRG1BP GEMIN2 HIF1A IL1A JRK KAT5 KEAP1 KPNB1 LMNA LMNB1 MAGED1 NMNAT1 NOP2 NUP50 POLR3C POM121 POU6F2 RAC1 RELB RNMT SKP2 SMARCB1 STAT1 STAT3 TAF9 ZNF131
Entrez ID		7690	23633
HPRD ID		07239	09465
Ensembl ID		ENSG00000172262	ENSG00000025800
Uniprot IDs		A0A024R087 P52739	O60684
PDB IDs			4UAD
Enriched GO Terms of Interacting Partners?
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