KPNA6 and ZNF131

Data Source:
BioGRID (pull down)

		KPNA6	ZNF131
Description		karyopherin subunit alpha 6	zinc finger protein 131
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Membrane Host Cell	Nucleoplasm Intermediate Filament Cytoskeleton
	Molecular Function	Protein Binding Nuclear Localization Sequence Binding Nuclear Import Signal Receptor Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Metal Ion Binding
	Biological Process	NLS-bearing Protein Import Into Nucleus Viral Genome Replication Mitigation Of Host Defenses By Symbiont Positive Regulation Of Transcription By RNA Polymerase II Maternal Process Involved In Female Pregnancy Entry Of Viral Genome Into Host Nucleus Through Nuclear Pore Complex Via Importin Positive Regulation Of Cytokine Production Involved In Inflammatory Response Positive Regulation Of Viral Life Cycle	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II
Pathways			SUMOylation of transcription cofactors
Drugs
Diseases
GWAS		Body mass index ( 26426971)	Body mass index ( 25673413) Mean corpuscular hemoglobin concentration ( 32888494) Menarche (age at onset) ( 25231870)
Interacting Genes		37 interacting genes: ANKRD11 ANP32A ANP32B ARNT BRCA1 CDKN1B CREBBP CSE1L DCPS EPAS1 FAM90A1 FRG1BP GEMIN2 HIF1A IL1A JRK KAT5 KEAP1 KPNB1 LMNA LMNB1 MAGED1 NMNAT1 NOP2 NUP50 POLR3C POM121 POU6F2 RAC1 RELB RNMT SKP2 SMARCB1 STAT1 STAT3 TAF9 ZNF131	9 interacting genes: EMSY FHL2 FHL5 HSPB1 KPNA2 KPNA3 KPNA6 MORN4 PIP4K2B
Entrez ID		23633	7690
HPRD ID		09465	07239
Ensembl ID		ENSG00000025800	ENSG00000172262
Uniprot IDs		O60684	A0A024R087 P52739
PDB IDs		4UAD
Enriched GO Terms of Interacting Partners?
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