VIPR1 and RAMP2

Data Source:
HPRD (in vitro)

		VIPR1	RAMP2
Description		vasoactive intestinal peptide receptor 1	receptor activity modifying protein 2
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Receptor Complex	Cytoplasm Lysosome Plasma Membrane Integral Component Of Plasma Membrane Clathrin-coated Pit Cell Surface Receptor Complex Amylin Receptor Complex 2 Adrenomedullin Receptor Complex
	Molecular Function	Vasoactive Intestinal Polypeptide Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity Peptide Hormone Binding	Adrenomedullin Receptor Activity Protein Binding Coreceptor Activity Amylin Receptor Activity Adrenomedullin Binding
	Biological Process	Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cell Population Proliferation	Angiogenesis Vasculogenesis Response To Hypoxia Sprouting Angiogenesis Calcium Ion Transport Intracellular Protein Transport G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Heart Development Female Pregnancy Regulation Of Blood Pressure Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Gene Expression Protein Transport Receptor Internalization Positive Regulation Of Protein Binding Response To Estradiol Response To Progesterone Cellular Response To Hormone Stimulus Adherens Junction Assembly Cellular Response To Vascular Endothelial Growth Factor Stimulus Negative Regulation Of Vascular Permeability Positive Regulation Of Angiogenesis Bicellular Tight Junction Assembly Basement Membrane Assembly Protein Localization To Plasma Membrane Vascular Associated Smooth Muscle Cell Development Amylin Receptor Signaling Pathway Adrenomedullin Receptor Signaling Pathway Negative Regulation Of Endothelial Cell Apoptotic Process Positive Regulation Of Vasculogenesis
Pathways		G alpha (s) signalling events Glucagon-type ligand receptors ADORA2B mediated anti-inflammatory cytokines production	G alpha (s) signalling events Calcitonin-like ligand receptors ADORA2B mediated anti-inflammatory cytokines production
Drugs			Pramlintide
Diseases
GWAS		Bipolar disorder ( 31043756) Cerebrospinal fluid clusterin levels ( 26545630) Hip circumference adjusted for BMI ( 28552196)	Pulse pressure ( 30224653)
Interacting Genes		16 interacting genes: ADCYAP1 CALM1 GNAI1 GNAQ GNAS GPRASP1 PFN1 PRDM5 PTMA RAMP1 RAMP2 RAMP3 SCT TINF2 VIP WASL	7 interacting genes: CALCA CALCRL CIDEB IAPP LCN2 SLC31A2 VIPR1
Entrez ID		7433	10266
HPRD ID		01890	05516
Ensembl ID		ENSG00000114812	ENSG00000131477
Uniprot IDs		A0A024R2N2 B4DNY6 P32241	A0A024R1Z2 O60895
PDB IDs		1OF2 1OGT 3B3I 3B6S 3DTX 3HCV 5DEF 5DEG 5IB1 5IB2 5IB3 5IB4 5IB5 6VN7	2XVT 3AQE 3AQF 4RWF 6UUN 6V2E
Enriched GO Terms of Interacting Partners?
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