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RAMP2 and LCN2
Data Source:
BioGRID
(two hybrid)
RAMP2
LCN2
Description
receptor activity modifying protein 2
lipocalin 2
Image
GO Annotations
Cellular Component
Cytoplasm
Lysosome
Plasma Membrane
Integral Component Of Plasma Membrane
Clathrin-coated Pit
Cell Surface
Receptor Complex
Amylin Receptor Complex 2
Adrenomedullin Receptor Complex
Extracellular Region
Extracellular Space
Specific Granule Lumen
Extracellular Exosome
Molecular Function
Adrenomedullin Receptor Activity
Protein Binding
Coreceptor Activity
Amylin Receptor Activity
Adrenomedullin Binding
Iron Ion Binding
Protein Binding
Small Molecule Binding
Identical Protein Binding
Enterobactin Binding
Biological Process
Angiogenesis
Vasculogenesis
Response To Hypoxia
Sprouting Angiogenesis
Calcium Ion Transport
Intracellular Protein Transport
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Heart Development
Female Pregnancy
Regulation Of Blood Pressure
Regulation Of G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Gene Expression
Protein Transport
Receptor Internalization
Positive Regulation Of Protein Binding
Response To Estradiol
Response To Progesterone
Cellular Response To Hormone Stimulus
Adherens Junction Assembly
Cellular Response To Vascular Endothelial Growth Factor Stimulus
Negative Regulation Of Vascular Permeability
Positive Regulation Of Angiogenesis
Bicellular Tight Junction Assembly
Basement Membrane Assembly
Protein Localization To Plasma Membrane
Vascular Associated Smooth Muscle Cell Development
Amylin Receptor Signaling Pathway
Adrenomedullin Receptor Signaling Pathway
Negative Regulation Of Endothelial Cell Apoptotic Process
Positive Regulation Of Vasculogenesis
Cellular Iron Ion Homeostasis
Apoptotic Process
Siderophore Transport
Cytokine-mediated Signaling Pathway
Antimicrobial Humoral Response
Defense Response To Bacterium
Neutrophil Degranulation
Innate Immune Response
Sequestering Of Iron Ion
Positive Regulation Of Cold-induced Thermogenesis
Pathways
G alpha (s) signalling events
Calcitonin-like ligand receptors
ADORA2B mediated anti-inflammatory cytokines production
Interleukin-4 and Interleukin-13 signaling
Neutrophil degranulation
Metal sequestration by antimicrobial proteins
Iron uptake and transport
Iron uptake and transport
Drugs
Pramlintide
Methyl nonanoate
2,3-Dihydroxy-Benzoic Acid
Carboxymycobactin S
2,3,-Dihydroxybenzoylserine
Carboxymycobactin T
Trencam-3,2-Hopo
Diseases
GWAS
Pulse pressure (
30224653
)
Interacting Genes
7 interacting genes:
CALCA
CALCRL
CIDEB
IAPP
LCN2
SLC31A2
VIPR1
61 interacting genes:
ALDH7A1
ALKBH4
ASB10
ASPH
BEX2
BMF
C20orf85
CAMLG
CCNC
CDSN
CHIC2
CLMP
CTDSP2
EHHADH
FAAP20
FAM25A
FAM25C
FAM25G
HDDC2
HGF
LAIR2
LNPEP
LRP2
LY96
MAGED4B
MMP2
MMP9
MSRB3
MYDGF
NDUFB2
NEIL2
ODAPH
P4HB
PDIA4
PELI1
PICK1
PIN1
POLL
POU4F2
PRKAA2
PTRH1
RAMP2
SCNM1
SEC61G
SGTA
SGTB
TBC1D21
TRAPPC2L
TRH
TRIAP1
TRIM32
TSG101
TTC23
TXN2
UBASH3A
UBE2F
UBQLN1
UBQLN2
VEZF1
XRN2
ZBED1
Entrez ID
10266
3934
HPRD ID
05516
02551
Ensembl ID
ENSG00000131477
ENSG00000148346
Uniprot IDs
A0A024R1Z2
O60895
P80188
PDB IDs
2XVT
3AQE
3AQF
4RWF
6UUN
6V2E
1DFV
1L6M
1NGL
1QQS
1X71
1X89
1X8U
3BY0
3CBC
3CMP
3DSZ
3DTQ
3FW4
3FW5
3HWD
3HWE
3HWF
3HWG
3I0A
3K3L
3PEC
3PED
3T1D
3TF6
3TZS
3U0D
4GH7
4IAW
4IAX
4K19
4MVI
4MVK
4MVL
4QAE
4ZFX
4ZHC
4ZHD
4ZHF
4ZHG
4ZHH
5JR8
5KHP
5KIC
5KID
5MHH
5N47
5N48
5NKN
6GQZ
6GR0
6O5D
6QMU
6S8V
6SUA
Enriched GO Terms of Interacting Partners
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