UPK1B and SIT1

Data Source:
BioGRID (two hybrid)

		UPK1B	SIT1
Description		uroplakin 1B	signaling threshold regulating transmembrane adaptor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane Integral Component Of Membrane Extracellular Exosome Apical Plasma Membrane Urothelial Plaque	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome
	Molecular Function	Structural Molecule Activity Protein Binding	Protein Binding Kinase Binding SH2 Domain Binding
	Biological Process	Response To Bacterium Epithelial Cell Differentiation	Adaptive Immune Response Signal Transduction T Cell Homeostasis Regulation Of T Cell Activation
Pathways
Drugs
Diseases
GWAS		Gemcitabine-induced early high-grade neutropenia in pancreatic cancer ( 30889042)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel) ( 23648065)
Interacting Genes		53 interacting genes: BCL2L13 BEST2 BNIP2 CD53 CD69 CERS4 CLDN7 DAGLA EDAR FAM209A FFAR2 FKBP7 FNDC9 GJA8 GJB1 GPR161 GPR37L1 GPX8 ISLR2 ITGB2 KASH5 KCNJ6 KIR2DL3 KLRC1 LMNA MFF MS4A4A NEMP1 PDZK1IP1 PIK3IP1 PLPP4 RHCG SAR1A SDHAF4 SHISA4 SIT1 SLC10A2 SLC16A2 SLC35C2 SLC39A2 SPINT1 SSMEM1 STX1A SYT9 TMEM139 TMEM237 TMEM262 TMEM45B TMEM54 TMEM91 TMUB2 UPK3A VSIG1	17 interacting genes: APOL2 BMP10 CLRN2 CSK FYN GRB2 ITM2A LCK MALL PLN PTPN11 SYK TMBIM6 TMEM140 TSPAN33 UPK1B ZAP70
Entrez ID		7348	27240
HPRD ID		03853	05394
Ensembl ID		ENSG00000114638	ENSG00000137078
Uniprot IDs		O75841	Q9Y3P8
PDB IDs
Enriched GO Terms of Interacting Partners?
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