UCHL3 and POGK

Data Source:
BioGRID (two hybrid)

		UCHL3	POGK
Description		ubiquitin C-terminal hydrolase L3	pogo transposable element derived with KRAB domain
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol	Nucleus Nucleoplasm
	Molecular Function	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Peptidase Activity NEDD8-specific Protease Activity Ubiquitin Binding	DNA Binding Protein Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Protein Deubiquitination Protein Phosphopantetheinylation Protein Catabolic Process Post-translational Protein Modification	Regulation Of Transcription, DNA-templated Multicellular Organism Development
Pathways		UCH proteinases Synthesis of active ubiquitin: roles of E1 and E2 enzymes Neddylation
Drugs
Diseases
GWAS		Diabetic retinopathy ( 23562823) Metabolite levels ( 23823483)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Post-traumatic stress disorder ( 25456346) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		20 interacting genes: ATM ATXN7L3 CDH1 FOXM1 LONRF1 NEDD8 NSG2 PJA1 PLA2G2A POGK RAD51 TRIM27 TRIM54 TRIM55 TRIM63 UBE2S USP15 USP21 USP28 XRCC5	2 interacting genes: APP UCHL3
Entrez ID		7347	57645
HPRD ID		04367	17872
Ensembl ID		ENSG00000118939	ENSG00000143157
Uniprot IDs		A0A087WTB8 A0A140VJZ4 P15374	A0A024R8Y1 B4DF62 Q9P215
PDB IDs		1UCH 1XD3 6ISU 6QML
Enriched GO Terms of Interacting Partners?
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