POGK and UCHL3

Data Source:
BioGRID (two hybrid)

		POGK	UCHL3
Description		pogo transposable element derived with KRAB domain	ubiquitin C-terminal hydrolase L3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleoplasm Cytoplasm Cytosol
	Molecular Function	DNA Binding Protein Binding	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Peptidase Activity NEDD8-specific Protease Activity Ubiquitin Binding
	Biological Process	Regulation Of Transcription, DNA-templated Multicellular Organism Development	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Protein Deubiquitination Protein Phosphopantetheinylation Protein Catabolic Process Post-translational Protein Modification
Pathways			UCH proteinases Synthesis of active ubiquitin: roles of E1 and E2 enzymes Neddylation
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Post-traumatic stress disorder ( 25456346) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Diabetic retinopathy ( 23562823) Metabolite levels ( 23823483)
Interacting Genes		2 interacting genes: APP UCHL3	20 interacting genes: ATM ATXN7L3 CDH1 FOXM1 LONRF1 NEDD8 NSG2 PJA1 PLA2G2A POGK RAD51 TRIM27 TRIM54 TRIM55 TRIM63 UBE2S USP15 USP21 USP28 XRCC5
Entrez ID		57645	7347
HPRD ID		17872	04367
Ensembl ID		ENSG00000143157	ENSG00000118939
Uniprot IDs		A0A024R8Y1 B4DF62 Q9P215	A0A087WTB8 A0A140VJZ4 P15374
PDB IDs			1UCH 1XD3 6ISU 6QML
Enriched GO Terms of Interacting Partners?
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