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PRR20C and NCK2
Data Source:
BioGRID
(two hybrid)
PRR20C
NCK2
Description
proline rich 20C
NCK adaptor protein 2
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Endoplasmic Reticulum
Cytosol
Vesicle Membrane
Postsynaptic Density
Molecular Function
Protein Binding
Phosphotyrosine Residue Binding
Protein Binding
Cytoskeletal Anchor Activity
Signaling Receptor Complex Adaptor Activity
Signaling Adaptor Activity
Protein-containing Complex Binding
Scaffold Protein Binding
Biological Process
Immunological Synapse Formation
Actin Filament Organization
Signal Transduction
Signal Complex Assembly
Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of Epidermal Growth Factor-activated Receptor Activity
Negative Regulation Of Cell Population Proliferation
Cell Migration
Lamellipodium Assembly
Positive Regulation Of Actin Filament Polymerization
Negative Regulation Of Peptidyl-serine Phosphorylation
Positive Regulation Of Translation In Response To Endoplasmic Reticulum Stress
Positive Regulation Of T Cell Proliferation
T Cell Activation
Positive Regulation Of Transcription By RNA Polymerase II
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Ephrin Receptor Signaling Pathway
Dendritic Spine Development
Positive Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of PERK-mediated Unfolded Protein Response
Negative Regulation Of Endoplasmic Reticulum Stress-induced EIF2 Alpha Phosphorylation
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress
Pathways
Downstream signal transduction
Nephrin family interactions
Ephrin signaling
Activation of RAC1
VEGFA-VEGFR2 Pathway
Regulation of cortical dendrite branching
Drugs
Diseases
GWAS
Addiction (
23533358
)
Anti-chlamydia trachomatis IgG seropositivity (
33204752
)
Mean platelet volume (
32888494
)
Platelet distribution width (
32888494
27863252
)
Systolic blood pressure in sickle cell anemia (
24058526
)
Interacting Genes
89 interacting genes:
ABI2
ANKHD1
ARID5A
ATXN1
BANP
BEND2
BHLHE40
BICRAL
C10orf55
C1orf94
C3orf36
CABP2
CCNK
CDC37
CELF4
DAZAP2
DMRT3
DVL3
EIF4ENIF1
ESRP1
FAM168A
FAM222B
FAM9A
FOXH1
FOXP3
GLIS2
GTF2A1
HIVEP1
HLX
HYPK
KRTAP19-1
KRTAP19-5
LASP1
MAGED1
MBNL3
NCK2
NFYC
NOTCH3
NTAQ1
OXER1
PATZ1
PHF1
PITX1
POGZ
POU2F1
POU6F2
PRR20A
PRR20B
PRR20D
PRR20E
PRR34
PRR35
PTTG2
RBM23
RBM42
RBPMS
RBPMS2
RHOXF2
RIPPLY1
RNF4
ROR2
SAMD11
SH3RF1
SIAH1
SMAP1
SNRPB
SNRPC
SP4
SRPK2
TBX3
TBX6
TCF7L2
TFG
THAP1
TIAL1
TLX3
TOLLIP
TPRX1
TRIM35
VAC14
VENTX
VEZF1
VPS37C
YPEL3
ZBTB32
ZC3H10
ZCCHC14
ZNF385C
ZNF683
171 interacting genes:
ABI1
ABI2
ABI3
ANKRD55
ANKS1B
ARHGAP32
ATN1
AXIN1
AXL
BCAR1
BCL11A
BTG1
C4orf17
CBARP
CBLB
CCDC120
CCDC33
CD3E
CHN1
CHN2
CIB1
CIPC
CLEC17A
CPSF6
CPSF7
CUEDC1
DDR1
DEFB124
DISC1
DLGAP4
DNM1
DOCK1
DOK1
DRAP1
DTX3
DVL1
EEF1G
EFHC2
EFNB1
EFNB2
EFS
EGFR
EIF3H
ERBB2
ERBB3
ERBB4
FAM124A
FAM47A
FAM53C
FAM83A
FASLG
FBXL19
FCRL2
FGFR1
FOSB
FXR2
FYB1
GAB1
GAREM1
GGN
HNRNPK
HOMEZ
HOXA1
HOXC4
HOXD8
HSF2BP
ILK
INCA1
INTS2
IRS1
KCTD17
KHDRBS1
KIAA0408
KIAA1217
KIT
KLHL24
KLHL35
KPRP
LCP2
LIMS1
LNX1
LRRIQ3
LZTS2
MAGEA6
MASP1
MBD6
MEOX2
MET
MIA3
MNT
MYPOP
NCKIPSD
NELFA
NET1
NFKBID
NHSL2
NPAS2
NPHS1
NR5A1
NTRK2
NUTM2F
ONECUT3
PAK1
PAK2
PBX4
PDGFRB
PHETA1
PIK3AP1
PKD1
PKN2
PRDM6
PRR16
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
PSMD10
PTK2
RASSF7
RBBP8NL
RBM26
REEP4
REL
SCML2
SCX
SF1
SF3A2
SF3B4
SHD
SKAP2
SMARCB1
SNW1
SOCS7
SORBS2
SOS1
SPATA2L
SPATC1L
SPRY2
SRMS
SRPK1
SRPK2
SSH3
SYNGAP1
SYNPO
TCF4
TCP10L
TMEM121
TNR
TRIM27
TRIM41
TRIP6
TXK
UBC
USP32
VARS2
VPS37B
WAS
WASF1
WASL
WBP11
WIPF1
WIPF2
ZBTB12
ZBTB42
ZBTB7B
ZC2HC1A
ZC2HC1B
ZNF341
ZNF526
ZNF688
Entrez ID
729240
8440
HPRD ID
19669
05378
Ensembl ID
ENSG00000229665
ENSG00000071051
Uniprot IDs
P86478
P86479
P86480
P86481
P86496
A0A0S2Z4M6
E7ERP6
O43639
PDB IDs
1U5S
1WX6
1Z3K
2B86
2CIA
2FRW
2FRY
2JXB
4E6R
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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