TUFM and DOC2A

Data Source:
BioGRID (affinity chromatography technology)

		TUFM	DOC2A
Description		Tu translation elongation factor, mitochondrial	double C2 domain alpha
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Membrane Mitochondrial Nucleoid Synapse Extracellular Exosome	Nucleoplasm Nucleolus Lysosome Cell Junction Neuron Projection Extrinsic Component Of Synaptic Vesicle Membrane
	Molecular Function	RNA Binding Translation Elongation Factor Activity GTPase Activity Protein Binding GTP Binding	Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding
	Biological Process	Translational Elongation Viral Process Response To Ethanol Mitochondrial Translational Elongation	Chemical Synaptic Transmission Nervous System Development Synaptic Vesicle Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Spontaneous Neurotransmitter Secretion
Pathways		Mitochondrial translation elongation
Drugs		Zinc Guanosine-5'-Diphosphate Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases		Combined oxidative phosphorylation deficiency (COXPD)
GWAS		Alcohol consumption (drinks per week) ( 30643258) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body fat percentage ( 26833246) Body mass index ( 20935630) Brain morphology (MOSTest) ( 32665545) Crohn's disease ( 28067908) Educational attainment ( 25201988) Estimated glomerular filtration rate ( 31152163) Extremely high intelligence ( 29520040) Hip circumference adjusted for BMI ( 25673412) Inflammatory bowel disease ( 28067908) Intelligence ( 28530673) Lamb consumption ( 32066663)	Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Height ( 28552196) Schizophrenia ( 28991256 25056061 29483656)
Interacting Genes		18 interacting genes: ARL6IP1 ASPH ATP6V1A CMTM5 DGAT2L6 EXOSC6 FAM9B FUNDC1 HMBOX1 LINC01554 MTIF3 MYH9 PCAT1 PTEN RHBDD2 SYP TNFRSF10D ZDHHC15	5 interacting genes: DYNLT1 RAP1GDS1 STXBP1 UBASH3B UNC13B
Entrez ID		7284	8448
HPRD ID		03861	05195
Ensembl ID		ENSG00000178952	ENSG00000149927
Uniprot IDs		A0A384ME17 P49411	Q14183
PDB IDs			4MJJ
Enriched GO Terms of Interacting Partners?
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