TUFM and ATP6V1A

Data Source:
HPRD (in vitro)

		TUFM	ATP6V1A
Description		Tu translation elongation factor, mitochondrial	ATPase H+ transporting V1 subunit A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Membrane Mitochondrial Nucleoid Synapse Extracellular Exosome	Nucleoplasm Lysosomal Membrane Cytosol Plasma Membrane Microvillus Apical Plasma Membrane Proton-transporting Two-sector ATPase Complex Proton-transporting V-type ATPase, V1 Domain Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	RNA Binding Translation Elongation Factor Activity GTPase Activity Protein Binding GTP Binding	ATP Binding ATPase Activity Proton-transporting ATP Synthase Activity, Rotational Mechanism Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process	Translational Elongation Viral Process Response To Ethanol Mitochondrial Translational Elongation	Cellular Iron Ion Homeostasis Insulin Receptor Signaling Pathway ATP Synthesis Coupled Proton Transport Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Cellular Response To Increased Oxygen Levels Phagosome Acidification Proton Transmembrane Transport
Pathways		Mitochondrial translation elongation	ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs		Zinc Guanosine-5'-Diphosphate Zinc acetate Zinc chloride Zinc sulfate, unspecified form	Alendronic acid Etidronic acid Tiludronic acid Bafilomycin A1 Bafilomycin B1
Diseases		Combined oxidative phosphorylation deficiency (COXPD)
GWAS		Alcohol consumption (drinks per week) ( 30643258) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body fat percentage ( 26833246) Body mass index ( 20935630) Brain morphology (MOSTest) ( 32665545) Crohn's disease ( 28067908) Educational attainment ( 25201988) Estimated glomerular filtration rate ( 31152163) Extremely high intelligence ( 29520040) Hip circumference adjusted for BMI ( 25673412) Inflammatory bowel disease ( 28067908) Intelligence ( 28530673) Lamb consumption ( 32066663)	Prostate cancer ( 23535732)
Interacting Genes		18 interacting genes: ARL6IP1 ASPH ATP6V1A CMTM5 DGAT2L6 EXOSC6 FAM9B FUNDC1 HMBOX1 LINC01554 MTIF3 MYH9 PCAT1 PTEN RHBDD2 SYP TNFRSF10D ZDHHC15	6 interacting genes: ANXA7 CDC42 CDKN1A SMN1 TK1 TUFM
Entrez ID		7284	523
HPRD ID		03861	06120
Ensembl ID		ENSG00000178952	ENSG00000114573
Uniprot IDs		A0A384ME17 P49411	P38606
PDB IDs
Enriched GO Terms of Interacting Partners?
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