RNF208 and STAC

Data Source:
BioGRID (two hybrid)

		RNF208	STAC
Description		ring finger protein 208	SH3 and cysteine rich domain
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol	Cytosol T-tubule Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding	Protein Binding Ion Channel Binding Metal Ion Binding
	Biological Process	Protein Autoubiquitination	Skeletal Muscle Contraction Signal Transduction Cellular Response To Heat Intracellular Signal Transduction Positive Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Cation Channel Activity
Pathways
Drugs
Diseases
GWAS			Age-related cognitive decline (global cognition) (slope of z-scores) ( 30954325) Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Arterial stiffness (brachial-femoral pulse wave velocity) ( 32790701) Asthma ( 29273806) Brooding (response to stress) ( 30886212) Celiac disease ( 23936387) Erectile dysfunction in type 1 diabetes ( 22704111) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Kidney disease (end stage renal disease vs non-end stage renal disease) in type 1 diabetes ( 31537649) Metabolite levels ( 23823483) Smoking behaviour (maximum cigarettes in a 24 hour period) ( 29532581)
Interacting Genes		18 interacting genes: BUD31 CREB5 DAZAP2 GRB2 HOXA1 KRTAP15-1 KRTAP26-1 LITAF OXER1 PIN1 RNF38 RPIA SH3RF1 STAC TRIM32 UBQLN1 UBQLN2 USP54	22 interacting genes: APP FBXO25 GOLGA2 KANK2 KIAA1958 LIMD1 LMNA LRRK2 LZTS2 MEOX2 NBPF19 NCKIPSD NEDD4L NOTCH2NLA PAX5 PAX6 PJA1 POU6F2 RNF208 STAT5B TRIP6 TRMO
Entrez ID		727800	6769
HPRD ID			11890
Ensembl ID		ENSG00000212864	ENSG00000144681
Uniprot IDs		Q9H0X6	B4DR96 B4DZ13 E9PEA7 Q8WUK8 Q99469
PDB IDs			2DL4 6B25
Enriched GO Terms of Interacting Partners?
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