TPO and TXNDC11

Data Source:
HPRD (in vivo)

		TPO	TXNDC11
Description		thyroid peroxidase	thioredoxin domain containing 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Cell Surface	Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Iodide Peroxidase Activity Peroxidase Activity Calcium Ion Binding Heme Binding	Protein Binding
	Biological Process	Thyroid Hormone Generation Response To Oxidative Stress Embryonic Hemopoiesis Hormone Biosynthetic Process Hydrogen Peroxide Catabolic Process Cellular Oxidant Detoxification
Pathways		Thyroxine biosynthesis
Drugs		Carbimazole Dextrothyroxine Propylthiouracil Methimazole Triclosan Resorcinol 2-mercaptobenzothiazole
Diseases		Thyroid dyshormonogenesis; Dyshormogenetic goiter
GWAS		Autoimmune thyroid disease ( 32581359) Hypothyroidism ( 30367059 27182965) Medication use (thyroid preparations) ( 31015401) Placebo response in major depressive disorder (% change in symptom score) ( 28696415) Thrombin-activatable fibrinolysis inhibitor levels ( 29378355) Thyroid peroxidase antibody levels ( 24586183) Thyroid peroxidase antibody positivity ( 24722205 24586183) Thyroid stimulating hormone levels ( 32769997)	Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Plasma renin activity levels ( 29650764) Red cell distribution width ( 32888494) Rheumatoid arthritis ( 30423114 24390342) Triglyceride levels ( 32203549) Weight ( 28552196)
Interacting Genes		2 interacting genes: DUOX1 TXNDC11	21 interacting genes: ACAA1 ATXN7 CDKN1A DUOX1 DUOX2 GFI1B HSP90B1 KLHL38 KRT15 KRT18 MKRN3 NOS3 ORC5 RAB2B RACGAP1 RPS19 RPS6KA5 SOCS3 STAT5A TPO ZNF417
Entrez ID		7173	51061
HPRD ID		06000	07125
Ensembl ID		ENSG00000115705	ENSG00000153066
Uniprot IDs		P07202 Q502Y3 Q6P534	Q6PKC3
PDB IDs
Enriched GO Terms of Interacting Partners?
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