TPO

Description		thyroid peroxidase
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Cell Surface
	Molecular Function	Iodide Peroxidase Activity Peroxidase Activity Calcium Ion Binding Heme Binding
	Biological Process	Thyroid Hormone Generation Response To Oxidative Stress Embryonic Hemopoiesis Hormone Biosynthetic Process Hydrogen Peroxide Catabolic Process Cellular Oxidant Detoxification
Pathways		Thyroxine biosynthesis
Drugs		Carbimazole Dextrothyroxine Propylthiouracil Methimazole Triclosan Resorcinol 2-mercaptobenzothiazole
Diseases		Thyroid dyshormonogenesis; Dyshormogenetic goiter
GWAS		Autoimmune thyroid disease ( 32581359) Hypothyroidism ( 30367059 27182965) Medication use (thyroid preparations) ( 31015401) Placebo response in major depressive disorder (% change in symptom score) ( 28696415) Thrombin-activatable fibrinolysis inhibitor levels ( 29378355) Thyroid peroxidase antibody levels ( 24586183) Thyroid peroxidase antibody positivity ( 24722205 24586183) Thyroid stimulating hormone levels ( 32769997)
Novel Interacting Genes		1 novel interacting genes: DUSP6
Interacting Genes		2 interacting genes: DUOX1 TXNDC11
Entrez ID		7173
HPRD ID		06000
Ensembl ID		ENSG00000115705
Uniprot IDs		P07202 Q502Y3 Q6P534
PDB IDs
Enriched GO Terms of Interacting Partners?
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