TXNDC11 and DUOX2

Data Source:
HPRD (in vivo)

		TXNDC11	DUOX2
Description		thioredoxin domain containing 11	dual oxidase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane	Endoplasmic Reticulum Cytosol Plasma Membrane Cell Surface Apical Plasma Membrane Cell Junction Cell Leading Edge NADPH Oxidase Complex Apical Part Of Cell Extracellular Exosome
	Molecular Function	Protein Binding	Peroxidase Activity Calcium Ion Binding Protein Binding NAD(P)H Oxidase H2O2-forming Activity Superoxide-generating NAD(P)H Oxidase Activity Heme Binding
	Biological Process		Thyroid Hormone Generation Defense Response Response To Oxidative Stress Response To Virus Cytokine-mediated Signaling Pathway Cuticle Development Hormone Biosynthetic Process Superoxide Anion Generation Hydrogen Peroxide Catabolic Process Hydrogen Peroxide Biosynthetic Process Response To CAMP Positive Regulation Of Wound Healing Cellular Oxidant Detoxification Positive Regulation Of Cell Motility
Pathways			Thyroxine biosynthesis
Drugs
Diseases			Thyroid dyshormonogenesis; Dyshormogenetic goiter
GWAS		Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Plasma renin activity levels ( 29650764) Red cell distribution width ( 32888494) Rheumatoid arthritis ( 30423114 24390342) Triglyceride levels ( 32203549) Weight ( 28552196)
Interacting Genes		21 interacting genes: ACAA1 ATXN7 CDKN1A DUOX1 DUOX2 GFI1B HSP90B1 KLHL38 KRT15 KRT18 MKRN3 NOS3 ORC5 RAB2B RACGAP1 RPS19 RPS6KA5 SOCS3 STAT5A TPO ZNF417	1 interacting genes: TXNDC11
Entrez ID		51061	50506
HPRD ID		07125	05997
Ensembl ID		ENSG00000153066	ENSG00000140279
Uniprot IDs		Q6PKC3	Q9NRD8
PDB IDs
Enriched GO Terms of Interacting Partners?
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