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TPI1 and LIPT1
Data Source:
HPRD
(two hybrid)
TPI1
LIPT1
Description
triosephosphate isomerase 1
lipoyltransferase 1
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Nucleus
Cytosol
Extracellular Exosome
Cytoplasm
Mitochondrion
Mitochondrial Matrix
Molecular Function
Triose-phosphate Isomerase Activity
Protein Binding
Methylglyoxal Synthase Activity
Ubiquitin Protein Ligase Binding
Protein Homodimerization Activity
Protein Binding
Transferase Activity, Transferring Acyl Groups
Lipoyltransferase Activity
Biological Process
Gluconeogenesis
Glycolytic Process
Multicellular Organism Development
Methylglyoxal Biosynthetic Process
Glycerol Catabolic Process
Glyceraldehyde-3-phosphate Biosynthetic Process
Canonical Glycolysis
Cellular Protein Modification Process
Lipid Metabolic Process
Protein Lipoylation
Protein Phosphopantetheinylation
Cellular Nitrogen Compound Metabolic Process
Pathways
Glycolysis
Gluconeogenesis
Glyoxylate metabolism and glycine degradation
Drugs
Zinc
N-Hydroxy-4-Phosphono-Butanamide
2-Phosphoglycolic Acid
Phosphoglycolohydroxamic Acid
3-(2-Benzothiazolylthio)-1-Propanesulfonic Acid
[2(Formyl-Hydroxy-Amino)-Ethyl]-Phosphonic Acid
5-fluorotryptophan
2-Carboxyethylphosphonic Acid
tert-butanol
Dihydroxyacetone phosphate
1,4-Dithiothreitol
3-phospho-D-glyceric acid
3-(BUTYLSULPHONYL)-PROPANOIC ACID
Artenimol
Zinc acetate
Zinc chloride
Zinc sulfate, unspecified form
Lipoic acid
Diseases
Anemia due to disorders of glycolytic enzymes, including: Hexokinase (HK) deficiency; Phosphoglycerate kinase 1 (PGK1) deficiency; Triose-phosphate isomerase (TPI) deficiency; Glucose phosphate isomerase (GPI) deficiency; Bisphosphoglycerate mutase (BPGM) deficiency
GWAS
Blood protein levels (
30072576
)
Refractive error (
32231278
)
Bipolar disorder (
21926972
)
Interacting Genes
17 interacting genes:
APP
BDKRB2
CCL11
CDKN2A
CFL1
DDX24
EGFR
HTR2C
LIPT1
MAPK6
PCNA
POT1
SETDB1
SP1
TERF1
UCHL5
YWHAQ
2 interacting genes:
APP
TPI1
Entrez ID
7167
51601
HPRD ID
01833
17282
Ensembl ID
ENSG00000111669
ENSG00000144182
Uniprot IDs
P60174
Q53HE2
V9HWK1
Q9Y234
PDB IDs
1HTI
1KLG
1KLU
1WYI
2IAM
2IAN
2JK2
2VOM
4BR1
4E41
4POC
4POD
4UNK
4UNL
4ZVJ
6C2G
6D43
6NLH
6UP1
6UP5
6UP8
6UPF
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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