LIPT1 and TPI1

Data Source:
HPRD (two hybrid)

		LIPT1	TPI1
Description		lipoyltransferase 1	triosephosphate isomerase 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix	Extracellular Space Nucleus Cytosol Extracellular Exosome
	Molecular Function	Protein Binding Transferase Activity, Transferring Acyl Groups Lipoyltransferase Activity	Triose-phosphate Isomerase Activity Protein Binding Methylglyoxal Synthase Activity Ubiquitin Protein Ligase Binding Protein Homodimerization Activity
	Biological Process	Cellular Protein Modification Process Lipid Metabolic Process Protein Lipoylation Protein Phosphopantetheinylation Cellular Nitrogen Compound Metabolic Process	Gluconeogenesis Glycolytic Process Multicellular Organism Development Methylglyoxal Biosynthetic Process Glycerol Catabolic Process Glyceraldehyde-3-phosphate Biosynthetic Process Canonical Glycolysis
Pathways		Glyoxylate metabolism and glycine degradation	Glycolysis Gluconeogenesis
Drugs		Lipoic acid	Zinc N-Hydroxy-4-Phosphono-Butanamide 2-Phosphoglycolic Acid Phosphoglycolohydroxamic Acid 3-(2-Benzothiazolylthio)-1-Propanesulfonic Acid [2(Formyl-Hydroxy-Amino)-Ethyl]-Phosphonic Acid 5-fluorotryptophan 2-Carboxyethylphosphonic Acid tert-butanol Dihydroxyacetone phosphate 1,4-Dithiothreitol 3-phospho-D-glyceric acid 3-(BUTYLSULPHONYL)-PROPANOIC ACID Artenimol Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases			Anemia due to disorders of glycolytic enzymes, including: Hexokinase (HK) deficiency; Phosphoglycerate kinase 1 (PGK1) deficiency; Triose-phosphate isomerase (TPI) deficiency; Glucose phosphate isomerase (GPI) deficiency; Bisphosphoglycerate mutase (BPGM) deficiency
GWAS		Bipolar disorder ( 21926972)	Blood protein levels ( 30072576) Refractive error ( 32231278)
Interacting Genes		2 interacting genes: APP TPI1	17 interacting genes: APP BDKRB2 CCL11 CDKN2A CFL1 DDX24 EGFR HTR2C LIPT1 MAPK6 PCNA POT1 SETDB1 SP1 TERF1 UCHL5 YWHAQ
Entrez ID		51601	7167
HPRD ID		17282	01833
Ensembl ID		ENSG00000144182	ENSG00000111669
Uniprot IDs		Q9Y234	P60174 Q53HE2 V9HWK1
PDB IDs			1HTI 1KLG 1KLU 1WYI 2IAM 2IAN 2JK2 2VOM 4BR1 4E41 4POC 4POD 4UNK 4UNL 4ZVJ 6C2G 6D43 6NLH 6UP1 6UP5 6UP8 6UPF
Enriched GO Terms of Interacting Partners?
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