TPI1

Description		triosephosphate isomerase 1
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GO Annotations	Cellular Component	Extracellular Space Nucleus Cytosol Extracellular Exosome
	Molecular Function	Triose-phosphate Isomerase Activity Protein Binding Methylglyoxal Synthase Activity Ubiquitin Protein Ligase Binding Protein Homodimerization Activity
	Biological Process	Gluconeogenesis Glycolytic Process Multicellular Organism Development Methylglyoxal Biosynthetic Process Glycerol Catabolic Process Glyceraldehyde-3-phosphate Biosynthetic Process Canonical Glycolysis
Pathways		Glycolysis Gluconeogenesis
Drugs		Zinc N-Hydroxy-4-Phosphono-Butanamide 2-Phosphoglycolic Acid Phosphoglycolohydroxamic Acid 3-(2-Benzothiazolylthio)-1-Propanesulfonic Acid [2(Formyl-Hydroxy-Amino)-Ethyl]-Phosphonic Acid 5-fluorotryptophan 2-Carboxyethylphosphonic Acid tert-butanol Dihydroxyacetone phosphate 1,4-Dithiothreitol 3-phospho-D-glyceric acid 3-(BUTYLSULPHONYL)-PROPANOIC ACID Artenimol Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases		Anemia due to disorders of glycolytic enzymes, including: Hexokinase (HK) deficiency; Phosphoglycerate kinase 1 (PGK1) deficiency; Triose-phosphate isomerase (TPI) deficiency; Glucose phosphate isomerase (GPI) deficiency; Bisphosphoglycerate mutase (BPGM) deficiency
GWAS		Blood protein levels ( 30072576) Refractive error ( 32231278)
Interacting Genes		17 interacting genes: APP BDKRB2 CCL11 CDKN2A CFL1 DDX24 EGFR HTR2C LIPT1 MAPK6 PCNA POT1 SETDB1 SP1 TERF1 UCHL5 YWHAQ
Entrez ID		7167
HPRD ID		01833
Ensembl ID		ENSG00000111669
Uniprot IDs		P60174 Q53HE2 V9HWK1
PDB IDs		1HTI 1KLG 1KLU 1WYI 2IAM 2IAN 2JK2 2VOM 4BR1 4E41 4POC 4POD 4UNK 4UNL 4ZVJ 6C2G 6D43 6NLH 6UP1 6UP5 6UP8 6UPF
Enriched GO Terms of Interacting Partners?
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