TP53 and KDM1A

  • Data Source:
  • BioGRID (genetic interference, enzymatic study)

TP53

KDM1A

Description tumor protein p53 lysine demethylase 1A
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Brain morphology (min-P) ( 32665545)
  • Brain morphology (MOSTest) ( 32665545)
  • Cortical surface area (min-P) ( 32665545)
  • Cortical surface area (MOSTest) ( 32665545)
  • Cortical thickness (min-P) ( 32665545)
  • Cortical thickness (MOSTest) ( 32665545)
  • Gamma glutamyl transferase levels ( 29403010)
  • Global electrical heterogeneity phenotypes ( 29622589)
  • Pulse pressure ( 27841878)
  • Subcortical volume (min-P) ( 32665545)
  • Subcortical volume (MOSTest) ( 32665545)
Interacting Genes 489 interacting genes: ABL1 ACKR3 ACTA1 AGT AKAP5 AKT1 ANK2 ANKRD2 ANTKMT ANXA2 ANXA3 APBB2 APEX1 APOH APPL1 APTX ARAF ARID1A ARID3A ARIH2 ARL3 ARNT ASH2L ATF3 ATM ATR ATRX ATXN3 AURKA AXIN1 BAG5 BAG6 BAIAP2L1 BAK1 BANP BARD1 BAX BCCIP BCL2 BCL2L1 BCL2L12 BCL2L2 BCL6 BCR BLM BMP1 BRCA1 BRCA2 BRF1 BTBD2 BTK C10orf90 CABLES1 CABLES2 CAPG CAPN1 CARM1 CBLC CCDC106 CCL18 CCNA2 CCNG1 CCNH CCT5 CD40LG CDC14A CDC14B CDC25C CDC34 CDC42 CDK1 CDK2 CDK4 CDK5 CDK6 CDK7 CDK8 CDK9 CDKN1A CDKN2A CDKN2B CDKN2C CEBPZ CENPX CETP CHD3 CHEK1 CHEK2 CHUK COP1 COPS2 COPS3 COPS4 COPS5 COPS6 COPS7A COPS8 COX17 CR2 CRBN CREBBP CREBZF CRK CSNK1A1 CSNK1D CSNK2A1 CSNK2A2 CSNK2B CUL9 CXXC1 CYLD DAPK3 DAXX DCAF1 DDX20 DDX5 DGKZ DHCR24 DHFR DLEU1 DMTF1 DNAJB1 DNAJC7 DNMT3L DTL DVL2 E2F1 E4F1 EAF2 EEF2 EFEMP2 EGLN3 EGR1 EHMT1 EHMT2 EIF2AK2 EIF2S2 ELL ELL3 EP300 EPHA2 EPHA3 ERBB2 ERCC2 ERCC3 ERCC6 ERH ESR1 FBXO11 FBXO42 FBXW7 FCAMR FGFR4 FOS FOXO3 FXYD6 FZR1 GADD45A GNL3 GPS1 GPS2 GPX2 GRWD1 GSK3B GSTM4 GTF2H1 GTF2H4 GYS2 HABP4 HDAC1 HDAC2 HDAC3 HECTD3 HECW1 HEY1 HIF1A HINFP HIPK1 HIPK2 HMGA2 HMGB1 HMGB2 HNF4A HNRNPUL1 HSP90AA1 HSP90AB1 HSP90B1 HSPA1A HSPA9 HSPB1 HTT HUWE1 IFI16 IKBKB ING1 ING4 ING5 IRF7 ITPK1 JDP2 JUN KAT2A KAT2B KAT5 KAT6A KAT7 KAT8 KDM1A KDM4D KIAA0087 KLF4 KLF6 KMT5A KPNA2 KPNA4 KPNB1 LACTB LAMA4 LAMTOR5 LATS2 LDB3 MAD2L1BP MAGEA2 MAGEB18 MAML1 MAP2K3 MAP2K5 MAP3K1 MAPK1 MAPK10 MAPK14 MAPK3 MAPK8 MAPK9 MAPKAPK5 MDC1 MDH1 MDM2 MDM4 MED1 MED17 MED21 MEN1 MET MIF MKRN2 MNAT1 MNDA MPHOSPH6 MSL2 MSX1 MTA1 MTA2 MUC1 MUL1 MVP MYBBP1A MYC NABP1 NABP2 NAP1L1 NAT10 NCL NCOA1 NCOA2 NCOA3 NDN NEDD8 NEIL3 NF2 NFKBIA NFYA NFYB NGFR NMT1 NMT2 NOP53 NPM1 NQO1 NR0B2 NR3C1 NR4A1 NTHL1 OTUB1 OTUD5 PADI1 PAFAH1B3 PARP1 PBK PCDHA4 PDGFRA PDLIM7 PELI1 PELI2 PELP1 PER2 PHB PIAS1 PIAS2 PIAS4 PIN1 PLAGL1 PLCG2 PLK1 PLK3 PML PNP POLA1 PPA1 PPARGC1A PPIB PPM1D PPP1CA PPP1CC PPP1R13L PPP2CA PPP2R2B PPP4C PRIM1 PRKAB2 PRKCA PRKD1 PRKDC PRKN PRKRA PRMT1 PRPF8 PSMB3 PSMC5 PSMD11 PSMD4 PSME3 PTEN PTGS2 PTK2 PTTG1 RAB4A RAB7A RAD51 RANBP9 RAP1B RB1 RBBP6 RBCK1 RBPJ RCHY1 RELA RING1 RNF125 RNF128 RNF38 RPA1 RPS6KA1 RPS6KA2 RPS6KA3 RRM2 RRM2B RUNX3 S100A2 S100A4 S100A6 S100A8 S100B SAT1 SCAMP1 SERPINB9 SETD7 SFN SHISA5 SIN3A SIN3B SIRT1 SLC9A9 SMAD2 SMAD3 SMARCA4 SMARCB1 SMARCD1 SMN1 SMYD2 SNRPN SP1 SP3 SRC SRSF1 SSTR3 STAMBP STARD10 STAT6 STK11 STK4 STX5 SUB1 SULT1E1 SUMO1 SYVN1 TADA3 TAF1 TAF1A TAF1B TAF1C TAF9 TAF9B TBP TCF4 TEAD2 TEC TEP1 TFAP2A TFAP2C TFDP1 TFIP11 THAP12 THAP8 THRB TIAF1 TK1 TOP1 TOP1MT TOP2A TOP2B TOPORS TP53BP1 TP53BP2 TP53INP1 TP53RK TP63 TP73 TRIAP1 TRIM27 TRIM39 TRIM67 TSC22D1 TSG101 TTK TWIST1 TXN UBB UBE2A UBE2D1 UBE2D3 UBE2I UBE2K UBE2L3 UBE2M UBE2N UBE2Q1 UBE2V2 UBE3A UFD1 UHRF1 UHRF2 UIMC1 USP11 USP21 USP24 USP28 USP3 USP42 USP49 USP7 UTP14A VRK1 WDR33 WDR5 WDR82 WRN WT1 WWOX XAF1 XPO1 XRCC6 YBX1 YWHAG YWHAZ YY1 YY2 ZBTB2 ZBTB49 ZCCHC10 ZHX1 ZIC3 ZMIZ2 ZNF148 ZNF24 ZNF302 ZNF679 ZNF839 ZNHIT1 265 interacting genes: AKAP9 ANKEF1 ANKRD23 AP1G2 AR ARHGAP15 ARHGAP29 ASB10 ASB3 ASCC2 ATP5MF ATP6V1B1 BAHD1 BAIAP2 BATF BCAT1 BIRC2 BLZF1 BMP3 BRCA1 C18orf54 C4orf17 C8orf48 C8orf74 CAGE1 CARD10 CCDC121 CCDC14 CCDC172 CCDC33 CCDC74A CCDC74B CCDC90B CDC23 CDC5L CDCA4 CDCA5 CENPQ CEP162 CEP57 CEP70 CEP76 CFAP100 COIL CRBN CRLF3 CSNK2A1 CSNK2A2 CTBP1 DBF4B DNAAF4 DNAJA3 DNTTIP1 E2F1 ECI2 ELOF1 EXOC1 EXOC7 FAM161A FAM204A FAM9A FIGNL1 FYCO1 FYN GABPB2 GAS8 GATA3 GCC1 GDF9 GLYR1 GOLGA2 GOLGA6A GPATCH2L GSK3B GSTCD GTPBP2 H3-4 H3-5 H3C1 H3C14 HAUS1 HAUS3 HAUS6 HDAC1 HESX1 HOMER3 HOXA1 ID2 IFI35 IGFBP4 IK IKBIP IL16 IMMT INSM1 INTS2 ISL1 ITGB3BP ITSN2 JRK KANSL1 KASH5 KDM5B KIAA0408 KIFC3 KLC3 KLF3 KLHDC4 KRT15 KRT17 KRT19 KRT222 KRT31 KRT33B KRT35 KRT38 KRT39 KRT40 KRT6A KRT6B KRT7 L3MBTL3 LENG8 LINC02875 LOXL4 LZTS1 MALT1 MBD3 MBD4 MCPH1 MCRS1 METTL27 MLC1 MNS1 MTA3 MTF2 MTMR9 MTO1 MYC MYLIP NBPF15 NBPF26 NDUFA8 NDUFS1 NECAB2 NEFL NF2 NFE2L2 NMI NOSTRIN NR1H2 NR1H3 NR2C2 NR2E1 NRBF2 ODAD3 OFCC1 OIP5 OPA3 OTUB1 PBX4 PDCD5 PDE4DIP PEX7 PFDN5 PHC2 PHF19 PHF20L1 PHF21A PMF1 PNKP PPARD PPM1D PPP1R12A PRDM1 PRIM2 PSMC1 PSMC3 PTEN RASSF1 RASSF2 RASSF3 RASSF8 RCOR1 RCOR3 RIOK1 RNF10 RNF168 RPRD1A SAMD3 SEPTIN6 SERGEF SETDB1 SF3B2 SH3GLB2 SLU7 SMAD9 SMARCD1 SMN1 SNF8 SNX15 SOCS6 SPATA22 SPATA24 SPICE1 SPRY2 SPSB1 SPZ1 SRGAP3 SSX2IP STAT3 STX11 STX19 SUMO2 SUV39H1 TACC1 TADA3 TAL1 TDO2 TEDC2 TERF1 TEX35 TEX9 TFIP11 TLE5 TMEM266 TNFAIP1 TNNT2 TP53 TP53BP1 TP53BP2 TRAF4 TRIM39 TRIM54 TSACC TSC1 TTC23 TTC33 UBA3 UBASH3B UBE2I UCHL5 UNC119 UNKL USP28 USP7 VPS11 VPS37A VPS37B WASHC3 WDR83 ZBED1 ZBTB24 ZBTB39 ZCCHC17 ZFP28 ZNF280A ZNF333 ZNF436 ZNF451 ZNF480 ZNF581 ZNF641 ZNF71 ZNF829
Entrez ID 7157 23028
HPRD ID 01859 09800
Ensembl ID ENSG00000141510 ENSG00000004487
Uniprot IDs A0A087WT22 A0A087WXZ1 A0A087X1Q1 H2EHT1 K7PPA8 P04637 Q53GA5 O60341
PDB IDs 1A1U 1AIE 1C26 1DT7 1GZH 1H26 1HS5 1JSP 1KZY 1MA3 1OLG 1OLH 1PES 1PET 1SAE 1SAF 1SAK 1SAL 1TSR 1TUP 1UOL 1XQH 1YC5 1YCQ 1YCR 1YCS 2AC0 2ADY 2AHI 2ATA 2B3G 2BIM 2BIN 2BIO 2BIP 2BIQ 2F1X 2FEJ 2FOJ 2FOO 2GS0 2H1L 2H2D 2H2F 2H4F 2H4H 2H4J 2H59 2J0Z 2J10 2J11 2J1W 2J1X 2J1Y 2J1Z 2J20 2J21 2K8F 2L14 2LY4 2MEJ 2MWO 2MWP 2MWY 2MZD 2OCJ 2PCX 2RUK 2VUK 2WGX 2X0U 2X0V 2X0W 2XWR 2YBG 2YDR 2Z5S 2Z5T 3D05 3D06 3D07 3D08 3D09 3D0A 3DAB 3DAC 3IGK 3IGL 3KMD 3KZ8 3LW1 3OQ5 3PDH 3Q01 3Q05 3Q06 3SAK 3TG5 3TS8 3ZME 4AGL 4AGM 4AGN 4AGO 4AGP 4AGQ 4BUZ 4BV2 4HFZ 4HJE 4IBQ 4IBS 4IBT 4IBU 4IBV 4IBW 4IBY 4IBZ 4IJT 4KVP 4LO9 4LOE 4LOF 4MZI 4MZR 4QO1 4RP6 4RP7 4X34 4XR8 4ZZJ 5A7B 5AB9 5ABA 5AOI 5AOJ 5AOK 5AOL 5AOM 5BUA 5ECG 5G4M 5G4N 5G4O 5HOU 5HP0 5HPD 5LAP 5LGY 5MCT 5MCU 5MCV 5MCW 5MF7 5MG7 5MHC 5MOC 5O1A 5O1B 5O1C 5O1D 5O1E 5O1F 5O1G 5O1H 5O1I 5OL0 5UN8 5XZC 6FF9 6FJ5 6GGA 6GGB 6GGC 6GGD 6GGE 6GGF 6R5L 6RJZ 6RK8 6RKI 6RKK 6RKM 6RL3 6RL4 6RL6 6RM5 6RM7 6RWH 6RWI 6RWS 6RWU 6RX2 6RZ3 6S39 6S3C 6S40 6S9Q 6SHZ 6SI0 6SI1 6SI2 6SI3 6SI4 6SIN 6SIO 6SIP 6SIQ 6SL6 6SLV 6T58 6V4F 6V4H 6VQO 6VR1 6VR5 6VRM 6VRN 7BWN 2COM 2DW4 2EJR 2H94 2HKO 2IW5 2L3D 2UXN 2UXX 2V1D 2X0L 2XAF 2XAG 2XAH 2XAJ 2XAQ 2XAS 2Y48 2Z3Y 2Z5U 3ABT 3ABU 3ZMS 3ZMT 3ZMU 3ZMV 3ZMZ 3ZN0 3ZN1 4BAY 4CZZ 4KUM 4UV8 4UV9 4UVA 4UVB 4UVC 4UXN 4XBF 5AFW 5H6Q 5H6R 5IT3 5L3B 5L3C 5L3D 5L3E 5L3F 5L3G 5LBQ 5LGN 5LGT 5LGU 5LHG 5LHH 5LHI 5X60 5YJB 6E1F 6K3E 6KGK 6KGL 6KGM 6KGN 6KGO 6KGP 6KGQ 6KGR 6NQM 6NQU 6NR5 6S35 6TE1 6VYP 6W4K 7JJL 7JJM 7JK7
Enriched GO Terms of Interacting Partners?
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