Description |
tumor protein p53 |
nuclear receptor coactivator 1 |
Image |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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- Genistein
- Corticosterone
- Prinaberel
- ERB-196
- (2S)-3-(1-{[2-(2-CHLOROPHENYL)-5-METHYL-1,3-OXAZOL-4-YL]METHYL}-1H-INDOL-5-YL)-2-ETHOXYPROPANOIC ACID
- [5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-YL]ACETONITRILE
- 2-(5-HYDROXY-NAPHTHALEN-1-YL)-1,3-BENZOOXAZOL-6-OL
- TO-901317
- 1-CHLORO-6-(4-HYDROXYPHENYL)-2-NAPHTHOL
- 4-(4-HYDROXYPHENYL)-1-NAPHTHALDEHYDE OXIME
- 5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-CARBONITRILE
- GW-590735
- 3-BROMO-6-HYDROXY-2-(4-HYDROXYPHENYL)-1H-INDEN-1-ONE
- 3-(6-HYDROXY-NAPHTHALEN-2-YL)-BENZO[D]ISOOXAZOL-6-OL
- (1R,3R)-5-[(2E)-3-{(1S,3R)-2,2,3-trimethyl-3-[6,6,6-trifluoro-5-hydroxy-5-(trifluoromethyl)hex-3-yn-1-yl]cyclopentyl}prop-2-en-1-ylidene]cyclohexane-1,3-diol
- 3,20-Pregnanedione
- Indeglitazar
- (8alpha,10alpha,13alpha,17beta)-17-[(4-hydroxyphenyl)carbonyl]androsta-3,5-diene-3-carboxylic acid
- Myristic acid
- 1,3-CYCLOHEXANEDIOL, 4-METHYLENE-5-[(2E)-[(1S,3AS,7AS)-OCTAHYDRO-1-(5-HYDROXY-5-METHYL-1,3-HEXADIYNYL)-7A-METHYL-4H-INDEN-4-YLIDENE]ETHYLIDENE]-, (1R,3S,5Z)
- Aleglitazar
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Diseases |
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GWAS |
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- Asthma ( 29273806)
- Body fat distribution (arm fat ratio) ( 30664634)
- Body fat distribution (trunk fat ratio) ( 30664634)
- Body mass index ( 26426971)
- Body mass index (age <50) ( 26426971)
- Body mass index (age>50) ( 26426971)
- Body mass index x sex x age interaction (4df test) ( 26426971)
- Breast cancer ( 29058716)
- Breast Cancer in BRCA1 mutation carriers ( 29058716)
- Chromium levels ( 26025379)
- Cognitive function ( 28093568)
- Diffuse large B cell lymphoma ( 25261932)
- Hand grip strength ( 29691431)
- Lung adenocarcinoma ( 28604730)
- Lung cancer ( 28604730)
- Lung cancer in ever smokers ( 28604730)
- Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500)
- Waist circumference adjusted for body mass index ( 28448500)
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Interacting Genes |
489 interacting genes:
ABL1
ACKR3
ACTA1
AGT
AKAP5
AKT1
ANK2
ANKRD2
ANTKMT
ANXA2
ANXA3
APBB2
APEX1
APOH
APPL1
APTX
ARAF
ARID1A
ARID3A
ARIH2
ARL3
ARNT
ASH2L
ATF3
ATM
ATR
ATRX
ATXN3
AURKA
AXIN1
BAG5
BAG6
BAIAP2L1
BAK1
BANP
BARD1
BAX
BCCIP
BCL2
BCL2L1
BCL2L12
BCL2L2
BCL6
BCR
BLM
BMP1
BRCA1
BRCA2
BRF1
BTBD2
BTK
C10orf90
CABLES1
CABLES2
CAPG
CAPN1
CARM1
CBLC
CCDC106
CCL18
CCNA2
CCNG1
CCNH
CCT5
CD40LG
CDC14A
CDC14B
CDC25C
CDC34
CDC42
CDK1
CDK2
CDK4
CDK5
CDK6
CDK7
CDK8
CDK9
CDKN1A
CDKN2A
CDKN2B
CDKN2C
CEBPZ
CENPX
CETP
CHD3
CHEK1
CHEK2
CHUK
COP1
COPS2
COPS3
COPS4
COPS5
COPS6
COPS7A
COPS8
COX17
CR2
CRBN
CREBBP
CREBZF
CRK
CSNK1A1
CSNK1D
CSNK2A1
CSNK2A2
CSNK2B
CUL9
CXXC1
CYLD
DAPK3
DAXX
DCAF1
DDX20
DDX5
DGKZ
DHCR24
DHFR
DLEU1
DMTF1
DNAJB1
DNAJC7
DNMT3L
DTL
DVL2
E2F1
E4F1
EAF2
EEF2
EFEMP2
EGLN3
EGR1
EHMT1
EHMT2
EIF2AK2
EIF2S2
ELL
ELL3
EP300
EPHA2
EPHA3
ERBB2
ERCC2
ERCC3
ERCC6
ERH
ESR1
FBXO11
FBXO42
FBXW7
FCAMR
FGFR4
FOS
FOXO3
FXYD6
FZR1
GADD45A
GNL3
GPS1
GPS2
GPX2
GRWD1
GSK3B
GSTM4
GTF2H1
GTF2H4
GYS2
HABP4
HDAC1
HDAC2
HDAC3
HECTD3
HECW1
HEY1
HIF1A
HINFP
HIPK1
HIPK2
HMGA2
HMGB1
HMGB2
HNF4A
HNRNPUL1
HSP90AA1
HSP90AB1
HSP90B1
HSPA1A
HSPA9
HSPB1
HTT
HUWE1
IFI16
IKBKB
ING1
ING4
ING5
IRF7
ITPK1
JDP2
JUN
KAT2A
KAT2B
KAT5
KAT6A
KAT7
KAT8
KDM1A
KDM4D
KIAA0087
KLF4
KLF6
KMT5A
KPNA2
KPNA4
KPNB1
LACTB
LAMA4
LAMTOR5
LATS2
LDB3
MAD2L1BP
MAGEA2
MAGEB18
MAML1
MAP2K3
MAP2K5
MAP3K1
MAPK1
MAPK10
MAPK14
MAPK3
MAPK8
MAPK9
MAPKAPK5
MDC1
MDH1
MDM2
MDM4
MED1
MED17
MED21
MEN1
MET
MIF
MKRN2
MNAT1
MNDA
MPHOSPH6
MSL2
MSX1
MTA1
MTA2
MUC1
MUL1
MVP
MYBBP1A
MYC
NABP1
NABP2
NAP1L1
NAT10
NCL
NCOA1
NCOA2
NCOA3
NDN
NEDD8
NEIL3
NF2
NFKBIA
NFYA
NFYB
NGFR
NMT1
NMT2
NOP53
NPM1
NQO1
NR0B2
NR3C1
NR4A1
NTHL1
OTUB1
OTUD5
PADI1
PAFAH1B3
PARP1
PBK
PCDHA4
PDGFRA
PDLIM7
PELI1
PELI2
PELP1
PER2
PHB
PIAS1
PIAS2
PIAS4
PIN1
PLAGL1
PLCG2
PLK1
PLK3
PML
PNP
POLA1
PPA1
PPARGC1A
PPIB
PPM1D
PPP1CA
PPP1CC
PPP1R13L
PPP2CA
PPP2R2B
PPP4C
PRIM1
PRKAB2
PRKCA
PRKD1
PRKDC
PRKN
PRKRA
PRMT1
PRPF8
PSMB3
PSMC5
PSMD11
PSMD4
PSME3
PTEN
PTGS2
PTK2
PTTG1
RAB4A
RAB7A
RAD51
RANBP9
RAP1B
RB1
RBBP6
RBCK1
RBPJ
RCHY1
RELA
RING1
RNF125
RNF128
RNF38
RPA1
RPS6KA1
RPS6KA2
RPS6KA3
RRM2
RRM2B
RUNX3
S100A2
S100A4
S100A6
S100A8
S100B
SAT1
SCAMP1
SERPINB9
SETD7
SFN
SHISA5
SIN3A
SIN3B
SIRT1
SLC9A9
SMAD2
SMAD3
SMARCA4
SMARCB1
SMARCD1
SMN1
SMYD2
SNRPN
SP1
SP3
SRC
SRSF1
SSTR3
STAMBP
STARD10
STAT6
STK11
STK4
STX5
SUB1
SULT1E1
SUMO1
SYVN1
TADA3
TAF1
TAF1A
TAF1B
TAF1C
TAF9
TAF9B
TBP
TCF4
TEAD2
TEC
TEP1
TFAP2A
TFAP2C
TFDP1
TFIP11
THAP12
THAP8
THRB
TIAF1
TK1
TOP1
TOP1MT
TOP2A
TOP2B
TOPORS
TP53BP1
TP53BP2
TP53INP1
TP53RK
TP63
TP73
TRIAP1
TRIM27
TRIM39
TRIM67
TSC22D1
TSG101
TTK
TWIST1
TXN
UBB
UBE2A
UBE2D1
UBE2D3
UBE2I
UBE2K
UBE2L3
UBE2M
UBE2N
UBE2Q1
UBE2V2
UBE3A
UFD1
UHRF1
UHRF2
UIMC1
USP11
USP21
USP24
USP28
USP3
USP42
USP49
USP7
UTP14A
VRK1
WDR33
WDR5
WDR82
WRN
WT1
WWOX
XAF1
XPO1
XRCC6
YBX1
YWHAG
YWHAZ
YY1
YY2
ZBTB2
ZBTB49
ZCCHC10
ZHX1
ZIC3
ZMIZ2
ZNF148
ZNF24
ZNF302
ZNF679
ZNF839
ZNHIT1
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81 interacting genes:
AHR
ANKRD11
AR
ARID1A
ARNT
BCL3
CARM1
CCND1
CIITA
COPS5
CREBBP
CXADR
DDX17
DDX5
EP300
ESR1
ESR2
ESRRA
ESRRG
FOS
FOXA2
FOXO1
GTF2B
HIF1A
HNF1A
HNF4A
HNF4G
JUN
KANK2
KAT2B
MAPK1
NCOR1
NFKB1
NKX2-1
NR1H2
NR1H3
NR1H4
NR1I2
NR1I3
NR2F1
NR2F6
NR3C1
NR3C2
NR4A1
NR5A1
NR5A2
NR6A1
PAGR1
PGR
PPARA
PPARD
PPARG
PPARGC1A
PRMT1
PRMT2
PSMB9
RARA
RARB
RARG
RORA
RORB
RXRA
RXRB
SMARCC1
SMARCE1
SNW1
SRF
STAT3
STAT6
SUMO1
TBP
TEAD1
TEAD2
THRA
THRB
TP53
TRIM27
TRIP4
VDR
YWHAH
YWHAQ
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Entrez ID |
7157 |
8648 |
HPRD ID |
01859 |
04070 |
Ensembl ID |
ENSG00000141510
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ENSG00000084676
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Uniprot IDs |
A0A087WT22
A0A087WXZ1
A0A087X1Q1
H2EHT1
K7PPA8
P04637
Q53GA5
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Q15788
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PDB IDs |
1A1U
1AIE
1C26
1DT7
1GZH
1H26
1HS5
1JSP
1KZY
1MA3
1OLG
1OLH
1PES
1PET
1SAE
1SAF
1SAK
1SAL
1TSR
1TUP
1UOL
1XQH
1YC5
1YCQ
1YCR
1YCS
2AC0
2ADY
2AHI
2ATA
2B3G
2BIM
2BIN
2BIO
2BIP
2BIQ
2F1X
2FEJ
2FOJ
2FOO
2GS0
2H1L
2H2D
2H2F
2H4F
2H4H
2H4J
2H59
2J0Z
2J10
2J11
2J1W
2J1X
2J1Y
2J1Z
2J20
2J21
2K8F
2L14
2LY4
2MEJ
2MWO
2MWP
2MWY
2MZD
2OCJ
2PCX
2RUK
2VUK
2WGX
2X0U
2X0V
2X0W
2XWR
2YBG
2YDR
2Z5S
2Z5T
3D05
3D06
3D07
3D08
3D09
3D0A
3DAB
3DAC
3IGK
3IGL
3KMD
3KZ8
3LW1
3OQ5
3PDH
3Q01
3Q05
3Q06
3SAK
3TG5
3TS8
3ZME
4AGL
4AGM
4AGN
4AGO
4AGP
4AGQ
4BUZ
4BV2
4HFZ
4HJE
4IBQ
4IBS
4IBT
4IBU
4IBV
4IBW
4IBY
4IBZ
4IJT
4KVP
4LO9
4LOE
4LOF
4MZI
4MZR
4QO1
4RP6
4RP7
4X34
4XR8
4ZZJ
5A7B
5AB9
5ABA
5AOI
5AOJ
5AOK
5AOL
5AOM
5BUA
5ECG
5G4M
5G4N
5G4O
5HOU
5HP0
5HPD
5LAP
5LGY
5MCT
5MCU
5MCV
5MCW
5MF7
5MG7
5MHC
5MOC
5O1A
5O1B
5O1C
5O1D
5O1E
5O1F
5O1G
5O1H
5O1I
5OL0
5UN8
5XZC
6FF9
6FJ5
6GGA
6GGB
6GGC
6GGD
6GGE
6GGF
6R5L
6RJZ
6RK8
6RKI
6RKK
6RKM
6RL3
6RL4
6RL6
6RM5
6RM7
6RWH
6RWI
6RWS
6RWU
6RX2
6RZ3
6S39
6S3C
6S40
6S9Q
6SHZ
6SI0
6SI1
6SI2
6SI3
6SI4
6SIN
6SIO
6SIP
6SIQ
6SL6
6SLV
6T58
6V4F
6V4H
6VQO
6VR1
6VR5
6VRM
6VRN
7BWN
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1FM6
1FM9
1K4W
1K74
1K7L
1KV6
1N4H
1NQ7
1NRL
1P8D
1PZL
1RDT
1TFC
1U3R
1U3S
1X76
1X78
1X7B
1X7J
1XIU
1XV9
1XVP
1YY4
1YYE
1ZAF
2A3I
2C52
2FVJ
2GTK
2HBH
2HC4
2HCD
2HFP
2NPA
2NV7
2P54
2PRG
3BEJ
3BQD
3CTB
3CWD
3DCT
3DCU
3DR1
3ET1
3ET3
3FEI
3FEJ
3FUR
3FXV
3G8I
3G9E
3GYT
3GYU
3H0A
3HC5
3HC6
3HVL
3IPQ
3IPS
3IPU
3KMR
3LMP
3OKH
3OKI
3OLF
3OLL
3OLS
3OMK
3OMM
3OMO
3OMP
3OMQ
3OOF
3OOK
3P88
3P89
3QT0
3RUT
3RUU
3RVF
3S9S
3T03
3UU7
3UUA
3UUD
3V9Y
3VN2
4DK7
4DK8
4DM6
4DM8
4DQM
4F9M
4FGY
4G1D
4G1Y
4G1Z
4G20
4G21
4G2H
4HEE
4J5X
4JYG
4JYH
4JYI
4MG5
4MG6
4MG7
4MG8
4MG9
4MGA
4MGB
4MGC
4MGD
4RUJ
4RUP
4TUZ
4TV1
4UDA
4UDB
4Y29
5A86
5AVI
5AVL
5AZT
5DSH
5DV3
5DV6
5DV8
5DVC
5DWL
5E7V
5GTN
5GTO
5GTP
5HJS
5JI0
5JMM
5L7E
5L7G
5L7H
5MWP
5MWY
5MX7
5NKY
5NMA
5NMB
5NWM
5OW7
5OW9
5OWD
5Q0J
5Q0K
5Q0L
5Q0M
5Q0N
5Q0O
5Q0P
5Q0Q
5Q0R
5Q0S
5Q0T
5Q0U
5Q0V
5Q0W
5Q0X
5Q0Y
5Q0Z
5Q10
5Q11
5Q12
5Q13
5Q14
5Q15
5Q16
5Q18
5Q19
5Q1A
5Q1B
5Q1C
5Q1D
5Q1E
5Q1F
5Q1G
5Q1H
5Q1I
5X0R
5X8U
5X8W
5Y44
5YCN
5YCP
5YP6
6A5W
6A5X
6A5Y
6A5Z
6A60
6BNS
6E3G
6FO7
6FO8
6FO9
6FOB
6FOD
6GEV
6GG8
6HTY
6ICJ
6IJR
6IJS
6ILQ
6ITM
6JNR
6JQ7
6KTM
6KTN
6L96
6NX1
6P9F
6SSQ
6T2M
6U25
6W9H
6W9I
6XP9
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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