VTA1 and NBR1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		VTA1	NBR1
Description		vesicle trafficking 1	NBR1 autophagy cargo receptor
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GO Annotations	Cellular Component	Nucleoplasm Multivesicular Body Cytosol Endosome Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome	Phagophore Assembly Site Nucleoplasm Mitochondrion Mitochondrial Intermembrane Space Lysosome Late Endosome Autophagosome Cytosol Membrane Nuclear Body M Band Intracellular Membrane-bounded Organelle Receptor Complex
	Molecular Function	Protein Binding Protein C-terminus Binding	Protein Binding Zinc Ion Binding Ubiquitin Binding Mitogen-activated Protein Kinase Binding
	Biological Process	Protein Transport Endosomal Transport Macroautophagy Viral Life Cycle Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Multivesicular Body Sorting Pathway ESCRT III Complex Disassembly	Macroautophagy Regulation Of Bone Mineralization Regulation Of Stress-activated MAPK Cascade Negative Regulation Of Osteoblast Differentiation
Pathways		Budding and maturation of HIV virion Endosomal Sorting Complex Required For Transport (ESCRT)	Pexophagy Pexophagy
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease ( 30804561) Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444) FEV1 ( 30804560) Height ( 28552196) Lung function (FEV1/FVC) ( 30804560) Lung function (FVC) ( 30804560) Peak expiratory flow ( 30804560) Response to radiotherapy in nasopharyngeal carcinoma (acute oral mucositis) ( 32503578) Retinal vascular caliber ( 21060863)
Interacting Genes		22 interacting genes: APP BEX3 CBS CCNC CDK4 CHMP1A CHMP1B CHMP5 DPPA2 ERBB3 KCTD13 KLHL12 LYST MAGEA11 MBIP NBR1 NECAB2 RABAC1 RPIA TEAD4 ZBTB16 ZNRD2	22 interacting genes: ATXN1L AXIN1 CALM1 CIB1 FEZ1 GABARAP GABARAPL2 GSK3A GSK3B ITSN2 MAP1LC3A MAP1LC3B MAP2K4 METAP1 SQSTM1 SYT4 TTN UBC UBE2D2 UBE2D3 USP8 VTA1
Entrez ID		51534	4077
HPRD ID		09855	01326
Ensembl ID		ENSG00000009844	ENSG00000188554
Uniprot IDs		A0A087WY55 Q9NP79	A0A024R1V3 B7Z5R6 Q14596
PDB IDs		2LXL 2LXM 4TXP 4TXQ 4TXR 4U7E	1WJ6 2BKF 2CP8 2G4S 2L8J 2MGW 2MJ5 4OLE
Enriched GO Terms of Interacting Partners?
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